Neuroscience

Articles and news from the latest research reports.

Posts tagged psychology

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Half a dozen times each night, your slumbering body performs a remarkable feat of coordination.

During the deepest throes of sleep, the body’s support systems run on their own timetables. Nerve cells hum along in your brain, their chitchat generating slow waves that signal sleep’s nether stages. Yet, like buses and trains with overlapping routes but unsynchronized schedules, this neural conversation has little to say to your heart, which pumps blood to its own rhythm through the body’s arteries and veins. Air likewise skips into the nostrils and down the windpipe in seemingly random spits and spats. And muscle fluctuations that make the legs twitch come and go as if in a vacuum. Networks of muscles, of brain cells, of airways and lungs, of heart and vessels operate largely independently.

Every couple of hours, though, in as little as 30 seconds, the barriers break down. Suddenly, there’s synchrony. All the disjointed activity of deep sleep starts to connect with its surroundings. Each network — run via the group effort of its own muscular, cellular and molecular players — joins the larger team.

This change, marking the transition from deep to light sleep, has only recently been understood in detail — thanks to a new look at when and how the body’s myriad networks link up to form an übernetwork.

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Filed under bodily function brain interconnected systems networks neuroscience psychology networks of networks science

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Alzheimer’s Experts Provide Strategic Roadmap

This week, a strategic roadmap to help to the nation’s health care system cope with the impending public health crisis caused Alzheimer’s disease and related dementia will be published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. The plan aims to link the latest scientific findings with clinical care and bring together patients, families, scientists, pharmaceutical companies, regulatory agencies, and advocacy organizations behind a common set of prioritized goals. The consensus document is the outcome of a June meeting of leading Alzheimer’s researchers, advocates and clinicians, who gathered as part of the Marian S. Ware Alzheimer Program at the University of Pennsylvania.

Today, 5.4 million people are living with the disease, and more than 15 million Americans are caring for persons with Alzheimer’s and other dementias, according to the Alzheimer’s Association. Alzheimer’s disease is the sixth-leading cause of death in the United States and the only cause of death among the top 10 in the United States that cannot be prevented, cured, or even slowed.

"Our plan aims to provide good quality care for affected patients and families, advance our understanding of the pathophysiology and natural history of AD and other dementias, develop effective treatments to slow or prevent these diseases, and translate scientific advances successfully into policy and practice," the authors wrote.

(Source: nursing.upenn.edu)

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Filed under alzheimer alzheimer's disease brain neuroscience psychology science

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Study finds new benefit of coffee: It reduces pain
The surprising finding is based on a study involving 48 volunteers who agreed to spend 90 minutes performing fake computer tasks meant to mimic office work. The tasks were known to cause pain in the shoulders, neck, forearms and wrists, and the researchers wanted to compare how people with chronic pain and those who were pain-free tolerated the tasks.
As a matter of convenience, the scientists allowed people to drink coffee before taking the test “to avoid unpleasant effects of caffeine deprivation, e.g. decreased vigor and alertness, sleepiness, and fatigue,” they reported.
But when it came time to analyze the data, the researchers from Norway’s National Institute of Occupational Health and Oslo University Hospital noticed that the 19 people who drank coffee reported a lower intensity of pain than the 29 people who didn’t.
In the shoulders and neck, for instance, the average pain intensity was rated 41 (on a 100-point scale) among the coffee drinkers and 55 for the coffee abstainers. Similar gaps were found for all pain sites measured, and coffee’s apparent pain-mitigation effect held up regardless of whether the subjects had chronic pain or not.
The authors of the study, which was published this week in the journal BMC Research Notes, cautioned that since the study wasn’t designed to test coffee’s influence on pain, the results come with many uncertainties. For starters, the researchers don’t know how much coffee the coffee drinkers consumed before taking the computer tests. They also doubt that the coffee drinkers and abstainers were similar in all respects except for their java consumption. Problems like these tend to undermine the importance of the findings. But those reservations are unlikely to trouble the legions of coffee drinkers looking for any reason not to cut back on their daily caffeine habit.

Study finds new benefit of coffee: It reduces pain

The surprising finding is based on a study involving 48 volunteers who agreed to spend 90 minutes performing fake computer tasks meant to mimic office work. The tasks were known to cause pain in the shoulders, neck, forearms and wrists, and the researchers wanted to compare how people with chronic pain and those who were pain-free tolerated the tasks.

As a matter of convenience, the scientists allowed people to drink coffee before taking the test “to avoid unpleasant effects of caffeine deprivation, e.g. decreased vigor and alertness, sleepiness, and fatigue,” they reported.

But when it came time to analyze the data, the researchers from Norway’s National Institute of Occupational Health and Oslo University Hospital noticed that the 19 people who drank coffee reported a lower intensity of pain than the 29 people who didn’t.

In the shoulders and neck, for instance, the average pain intensity was rated 41 (on a 100-point scale) among the coffee drinkers and 55 for the coffee abstainers. Similar gaps were found for all pain sites measured, and coffee’s apparent pain-mitigation effect held up regardless of whether the subjects had chronic pain or not.

The authors of the study, which was published this week in the journal BMC Research Notes, cautioned that since the study wasn’t designed to test coffee’s influence on pain, the results come with many uncertainties. For starters, the researchers don’t know how much coffee the coffee drinkers consumed before taking the computer tests. They also doubt that the coffee drinkers and abstainers were similar in all respects except for their java consumption. Problems like these tend to undermine the importance of the findings. But those reservations are unlikely to trouble the legions of coffee drinkers looking for any reason not to cut back on their daily caffeine habit.

Filed under caffeine neuroscience brain psychology pain science

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Have you ever noticed how tiresome it can be to follow a conversation at a noisy party? Rest assured: this is not necessarily due to bad hearing – although that might make things worse. Scientists at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig have found that adverse listening situations are difficult for the brain, partly because they draw on the same, limited resources supporting our short-term memory. The new findings are particularly relevant to understanding the cognitive consequences of hearing damage, a condition that affects an increasing number of people.

Have you ever noticed how tiresome it can be to follow a conversation at a noisy party? Rest assured: this is not necessarily due to bad hearing – although that might make things worse. Scientists at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig have found that adverse listening situations are difficult for the brain, partly because they draw on the same, limited resources supporting our short-term memory. The new findings are particularly relevant to understanding the cognitive consequences of hearing damage, a condition that affects an increasing number of people.

Filed under memory STM neuroscience brain psychology noise hearing

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Brain Networks of Explicit and Implicit Learning
Are explicit versus implicit learning mechanisms reflected in the brain as distinct neural structures, as previous research indicates, or are they distinguished by brain networks that involve overlapping systems with differential connectivity? In this functional MRI study we examined the neural correlates of explicit and implicit learning of artificial grammar sequences. Using effective connectivity analyses we found that brain networks of different connectivity underlie the two types of learning: while both processes involve activation in a set of cortical and subcortical structures, explicit learners engage a network that uses the insula as a key mediator whereas implicit learners evoke a direct frontal-striatal network. Individual differences in working memory also differentially impact the two types of sequence learning.

Brain Networks of Explicit and Implicit Learning

Are explicit versus implicit learning mechanisms reflected in the brain as distinct neural structures, as previous research indicates, or are they distinguished by brain networks that involve overlapping systems with differential connectivity? In this functional MRI study we examined the neural correlates of explicit and implicit learning of artificial grammar sequences. Using effective connectivity analyses we found that brain networks of different connectivity underlie the two types of learning: while both processes involve activation in a set of cortical and subcortical structures, explicit learners engage a network that uses the insula as a key mediator whereas implicit learners evoke a direct frontal-striatal network. Individual differences in working memory also differentially impact the two types of sequence learning.

Filed under brain neuroscience psychology learning learning mechanisms explicit implicit science

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Previously existing ideas on how advanced maternal age affects adult health of children have to be reconsidered. It had been thought that mothers delivering later in life have children that are less healthy as adults, because the body of the mother had already degenerated due to physiological effects like decreasing oocyte quality or a weakened placenta. In fact, what affects the health of the grown-up children is not the age of their mother but her education and the number of years she survives after giving birth and thus spends with her offspring. This is the conclusion of a new study by Mikko Myrskylä from the Max Planck Institute for Demographic Research in Rostock, Germany carried out with data from 18,000 US children and their mothers.

Previously existing ideas on how advanced maternal age affects adult health of children have to be reconsidered. It had been thought that mothers delivering later in life have children that are less healthy as adults, because the body of the mother had already degenerated due to physiological effects like decreasing oocyte quality or a weakened placenta. In fact, what affects the health of the grown-up children is not the age of their mother but her education and the number of years she survives after giving birth and thus spends with her offspring. This is the conclusion of a new study by Mikko Myrskylä from the Max Planck Institute for Demographic Research in Rostock, Germany carried out with data from 18,000 US children and their mothers.

Filed under maternal age neuroscience psychology health science

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Researchers use characteristic differences in eye movements to identify patients with deficits in neurological function.
Observing patients’ eye movements may hold clues about neurological functioning. In a study published last month (August 25) in the Journal of Neurology, scientists show that subtle differences in eye movement patterns can be utilized to identify patients with Parkinson’s, fetal alcohol syndrome, or attention deficit disorder, providing hope for a quick and noninvasive strategy to aid in diagnosing these, and possibly other, neurological diseases.
“I am very impressed with the use of this eye tracking as a potential behavioral biomarker,” said Edward Riley, who studies fetal alcohol syndrome at San Diego State University, but did not participate in the research. The strategy could one day be used to rapidly screen children at risk for behavioral problems, he added, but whose mild symptoms may cause their issues to be overlooked.
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Researchers use characteristic differences in eye movements to identify patients with deficits in neurological function.

Observing patients’ eye movements may hold clues about neurological functioning. In a study published last month (August 25) in the Journal of Neurology, scientists show that subtle differences in eye movement patterns can be utilized to identify patients with Parkinson’s, fetal alcohol syndrome, or attention deficit disorder, providing hope for a quick and noninvasive strategy to aid in diagnosing these, and possibly other, neurological diseases.

“I am very impressed with the use of this eye tracking as a potential behavioral biomarker,” said Edward Riley, who studies fetal alcohol syndrome at San Diego State University, but did not participate in the research. The strategy could one day be used to rapidly screen children at risk for behavioral problems, he added, but whose mild symptoms may cause their issues to be overlooked.

Read more

Filed under eye movements neurological disorders neuroscience brain psychology science

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Every activity in the brain involves the transfer of signals between neurons. Frequently, as many as one thousand signals rain down on a single neuron simultaneously. To ensure that precise signals are delivered, the brain possesses a sophisticated inhibitory system. Stefan Remy and colleagues at the German Center for Neurodegenerative Diseases and the University Bonn have illuminated how this system works.
“The system acts like a filter, only letting the most important impulses pass,” explains Remy. “This produces the targeted neuronal patterns that are indispensible for long-term memory storage.”

Every activity in the brain involves the transfer of signals between neurons. Frequently, as many as one thousand signals rain down on a single neuron simultaneously. To ensure that precise signals are delivered, the brain possesses a sophisticated inhibitory system. Stefan Remy and colleagues at the German Center for Neurodegenerative Diseases and the University Bonn have illuminated how this system works.

“The system acts like a filter, only letting the most important impulses pass,” explains Remy. “This produces the targeted neuronal patterns that are indispensible for long-term memory storage.”

Filed under neuroscience brain psychology memory neuronal inhibition neuron science

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A new study led by MIT neuroscientists has found that brain scans of patients with social anxiety disorder can help predict whether they will benefit from cognitive behavioral therapy.
Social anxiety is usually treated with either cognitive behavioral therapy or medications. However, it is currently impossible to predict which treatment will work best for a particular patient. The team of researchers from MIT, Boston University (BU) and Massachusetts General Hospital (MGH) found that the effectiveness of therapy could be predicted by measuring patients’ brain activity as they looked at photos of faces, before the therapy sessions began.
The findings, published this week in the Archives of General Psychiatry, may help doctors choose more effective treatments for social anxiety disorder, which is estimated to affect around 15 million people in the United States.

A new study led by MIT neuroscientists has found that brain scans of patients with social anxiety disorder can help predict whether they will benefit from cognitive behavioral therapy.

Social anxiety is usually treated with either cognitive behavioral therapy or medications. However, it is currently impossible to predict which treatment will work best for a particular patient. The team of researchers from MIT, Boston University (BU) and Massachusetts General Hospital (MGH) found that the effectiveness of therapy could be predicted by measuring patients’ brain activity as they looked at photos of faces, before the therapy sessions began.

The findings, published this week in the Archives of General Psychiatry, may help doctors choose more effective treatments for social anxiety disorder, which is estimated to affect around 15 million people in the United States.

Filed under CBT brain neuroscience psychology social anxiety science

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