Neuroscience

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Posts tagged neurotransmitters

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A: Fueling all this brain activity, and the basis for some imaging techniques, is a dense network of delicate blood vessels.

B: Neurons communicate with one another by releasing chemicals, such as dopamine, from pouches called vesicles. The vesicles, seen here in a fibroblast cell, have a geodesic outer coating that eventually pops through the side of the cell and releases its chemical message to be detected by the cell’s neighbors.

C: Our cells are surrounded by a scaffold of proteins that maintains a cell’s shape. Under an electron microscope, protein fibers called actin filaments look like braided ropes.

D: A few years ago, neuroscientists figured out how to take two fluorescent proteins that glowed in green or red and turn them into a rainbow of different colors that can be incorporated into individual neurons. Here the technique is used to stain cells in the cerebellum. The result? A “brainbow.”

Source: Portraits of the Mind: Visualizing the Brain from Antiquity to the 21st Century

Filed under brain cells cerebellum dopamine mind neuron neuroscience neurotransmitters protein psychology science illustration

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To investigate membrane fusion during synaptic transmission (top), Rothman, Pincet, and colleagues designed an artificial version of the event. They exposed lipid nanodiscs embedded with SNARE proteins to vesicles containing complementary SNARE proteins. Only one SNARE protein complex was required for fusion between the discs and vesicles (A), but three were necessary to create a stable pore to release the neurotransmitter contained within the vesicle (B).

SNAREs at the Synapse

To investigate membrane fusion during synaptic transmission (top), Rothman, Pincet, and colleagues designed an artificial version of the event. They exposed lipid nanodiscs embedded with SNARE proteins to vesicles containing complementary SNARE proteins. Only one SNARE protein complex was required for fusion between the discs and vesicles (A), but three were necessary to create a stable pore to release the neurotransmitter contained within the vesicle (B).

SNAREs at the Synapse

Filed under SNARE brain neuron neuroscience neurotransmitters proteins psychology science synapse synaptic transmission cells membrane

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