Neuroscience

Articles and news from the latest research reports.

Posts tagged neuroscience

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Like a melody that keeps playing in your head even after the music stops, researchers at the University of Illinois’s Beckman Institute have shown that the beat goes on when it comes to the human visual system.
In an experiment designed to test their theory about a brain mechanism involved in visual processing, the researchers used periodic visual stimuli and electroencephalogram (EEG) recordings and found, one, that they could precisely time the brain’s natural oscillations to future repetitions of the event, and, two, that the effect occurred even after the prompting stimuli was discontinued. These rhythmic oscillations lead to a heightened visual awareness of the next event, meaning controlling them could lead to better visual processing when it matters most, such as in environments like air traffic control towers.

Like a melody that keeps playing in your head even after the music stops, researchers at the University of Illinois’s Beckman Institute have shown that the beat goes on when it comes to the human visual system.

In an experiment designed to test their theory about a brain mechanism involved in visual processing, the researchers used periodic visual stimuli and electroencephalogram (EEG) recordings and found, one, that they could precisely time the brain’s natural oscillations to future repetitions of the event, and, two, that the effect occurred even after the prompting stimuli was discontinued. These rhythmic oscillations lead to a heightened visual awareness of the next event, meaning controlling them could lead to better visual processing when it matters most, such as in environments like air traffic control towers.

Filed under brain brainwaves neuroscience psychology science vision consciousness

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Marketers are using neuroscience to create advertising which speaks directly to your brain.
How do you decide which running shoes to buy? Why do you prefer the iPhone over all other smart phones? Why did smokers crave a cigarette after watching an ad designed to turn people off smoking, while non-smokers were disgusted by it? These are the questions advertisers, marketers and market researchers are constantly faced with and Swinburne Neuroscience Professor Richard Silberstein has some of the answers.
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Marketers are using neuroscience to create advertising which speaks directly to your brain.

How do you decide which running shoes to buy? Why do you prefer the iPhone over all other smart phones? Why did smokers crave a cigarette after watching an ad designed to turn people off smoking, while non-smokers were disgusted by it? These are the questions advertisers, marketers and market researchers are constantly faced with and Swinburne Neuroscience Professor Richard Silberstein has some of the answers.

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Filed under science neuromarketing neuroscience advertising emotion SST communication

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Zebrafish Study Explains Why the Circadian Rhythm Affects Your Health
The circadian rhythm is regulated by a “clock” that reacts to both incoming light and genetic factors.
In an article now being published in the scientific journal Cell Reports, it is demonstrated for the first time that disruption of the circadian rhythm immediately inhibit blood vessel growth in zebra fish embryos.
During experiments with hours-old zebra fish embryos, the researchers manipulated their circadian rhythm through exposing them to lighting conditions varying from constant darkness to constant light. The growth of blood vessels in the various groups was then studied. The results showed that exposure to constant light (1800 lux) markedly impaired blood vessel growth; additionally, it affected the expression of genes that regulate the circadian clock.
"The results can definitely be translated into clinical circumstances. Individuals with disrupted circadian rhythms — for example, shift workers who work under artificial lights at night, people with sleeping disorders or a genetic predisposition — should be on guard against illnesses associated with disrupted blood vessel growth," says Lasse Dahl Jensen, researcher in Cardiovascular Physiology at Linköping University (LiU), and lead writer of the article.
Such diseases include heart attack, stroke, chronic inflammation, and cancer. Disruptions in blood vessel growth can also affect fetal development, women’s reproductive cycles, and the healing of wounds.

Zebrafish Study Explains Why the Circadian Rhythm Affects Your Health

The circadian rhythm is regulated by a “clock” that reacts to both incoming light and genetic factors.

In an article now being published in the scientific journal Cell Reports, it is demonstrated for the first time that disruption of the circadian rhythm immediately inhibit blood vessel growth in zebra fish embryos.

During experiments with hours-old zebra fish embryos, the researchers manipulated their circadian rhythm through exposing them to lighting conditions varying from constant darkness to constant light. The growth of blood vessels in the various groups was then studied. The results showed that exposure to constant light (1800 lux) markedly impaired blood vessel growth; additionally, it affected the expression of genes that regulate the circadian clock.

"The results can definitely be translated into clinical circumstances. Individuals with disrupted circadian rhythms — for example, shift workers who work under artificial lights at night, people with sleeping disorders or a genetic predisposition — should be on guard against illnesses associated with disrupted blood vessel growth," says Lasse Dahl Jensen, researcher in Cardiovascular Physiology at Linköping University (LiU), and lead writer of the article.

Such diseases include heart attack, stroke, chronic inflammation, and cancer. Disruptions in blood vessel growth can also affect fetal development, women’s reproductive cycles, and the healing of wounds.

Filed under blood vessels brain circadian rhythms health neuroscience psychology science diseases

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 Metabolism in the brain fluctuates with circadian rhythm 
A new study reveals that the brain clock itself is driven, in part, by metabolism, the production and flow of chemical energy in cells. The researchers focused primarily on a phenomenon known as “redox” in tissues of the SCN from the brains of rats and mice.
Redox represents the energy changes of cellular metabolism (usually through the transfer of electrons). When a molecule gains one or more electrons, scientists call it a reduction; when it loses electrons, they say it is oxidized. These redox reactions, the researchers found, oscillate on a 24-hour cycle in the brain clock, and literally open and close channels of communication in brain cells.
“The language of the brain is electrical; it determines what kind of signals one part of the brain sends to the other cells in its tissue, as well as the other parts of the brain nearby,” said University of Illinois cell and developmental biology professor Martha Gillette, who led the study. “The fundamental discovery here is that there is an intrinsic oscillation in metabolism in the clock region of the brain that takes place without external intervention. And this change in metabolism determines the excitable state of that part of the brain.”
The new findings alter basic assumptions about how the brain works, Gillette said.
“Basically, the idea has always been that metabolism is serving brain function. What we’re showing is metabolism is part of brain function,” she said. “Our study implies that changes in cellular metabolic state could be a cause, rather than a result, of neuronal activity.”
Metabolism in the brain fluctuates with circadian rhythm

A new study reveals that the brain clock itself is driven, in part, by metabolism, the production and flow of chemical energy in cells. The researchers focused primarily on a phenomenon known as “redox” in tissues of the SCN from the brains of rats and mice.

Redox represents the energy changes of cellular metabolism (usually through the transfer of electrons). When a molecule gains one or more electrons, scientists call it a reduction; when it loses electrons, they say it is oxidized. These redox reactions, the researchers found, oscillate on a 24-hour cycle in the brain clock, and literally open and close channels of communication in brain cells.

“The language of the brain is electrical; it determines what kind of signals one part of the brain sends to the other cells in its tissue, as well as the other parts of the brain nearby,” said University of Illinois cell and developmental biology professor Martha Gillette, who led the study.
“The fundamental discovery here is that there is an intrinsic oscillation in metabolism in the clock region of the brain that takes place without external intervention. And this change in metabolism determines the excitable state of that part of the brain.”

The new findings alter basic assumptions about how the brain works, Gillette said.

“Basically, the idea has always been that metabolism is serving brain function. What we’re showing is metabolism is part of brain function,” she said. “Our study implies that changes in cellular metabolic state could be a cause, rather than a result, of neuronal activity.”

Filed under brain circadian rhythms metabolism neuroscience psychology science

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The connections between the rising rates of chronic disease and the production and consumption of modern foods can no longer be ignored. Our food supply is not healthy, nor is it sustainable. It has changed so dramatically that we have yet to adapt to the changes. Our food supply has been completely adulterated over the past few decades alone, more drastically than during any other time in history.
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The connections between the rising rates of chronic disease and the production and consumption of modern foods can no longer be ignored. Our food supply is not healthy, nor is it sustainable. It has changed so dramatically that we have yet to adapt to the changes. Our food supply has been completely adulterated over the past few decades alone, more drastically than during any other time in history.

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Filed under evolution food health neuroscience nutrition psychology science diseases

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Vanderbilt University researchers studying interventions for adolescents and young adults with autism are reporting that there is insufficient evidence to support findings, good or bad, for the therapies currently used.
The researchers systematically screened more than 4,500 studies and reviewed the 32 studies published from January 1980 to December 2011 on therapies for people ages 13 to 30 with autism spectrum disorders. They focused on the outcomes, including harms and adverse effects, of interventions, including medical, behavioral, educational and vocational.

• Some evidence revealed that treatments could improve social skills and educational outcomes such as vocabulary or reading, but the studies were generally small and had limited follow-up.
• Limited evidence supports the use of medical interventions in adolescents and young adults with autism. The most consistent findings were identified for the effects of antipsychotic medications on reducing problem behaviors that tend to occur with autism, such as irritability and aggression. Harms associated with medications included sedation and weight gain.
• Only five articles tested vocational interventions, all of which suggested that certain vocational interventions may be effective for certain individuals, but each study had significant flaws that limited the researchers’ confidence in their conclusions.

A Systematic Review of Vocational Interventions for Young Adults With Autism Spectrum Disorders

Vanderbilt University researchers studying interventions for adolescents and young adults with autism are reporting that there is insufficient evidence to support findings, good or bad, for the therapies currently used.

The researchers systematically screened more than 4,500 studies and reviewed the 32 studies published from January 1980 to December 2011 on therapies for people ages 13 to 30 with autism spectrum disorders. They focused on the outcomes, including harms and adverse effects, of interventions, including medical, behavioral, educational and vocational.

• Some evidence revealed that treatments could improve social skills and educational outcomes such as vocabulary or reading, but the studies were generally small and had limited follow-up.

• Limited evidence supports the use of medical interventions in adolescents and young adults with autism. The most consistent findings were identified for the effects of antipsychotic medications on reducing problem behaviors that tend to occur with autism, such as irritability and aggression. Harms associated with medications included sedation and weight gain.

• Only five articles tested vocational interventions, all of which suggested that certain vocational interventions may be effective for certain individuals, but each study had significant flaws that limited the researchers’ confidence in their conclusions.

A Systematic Review of Vocational Interventions for Young Adults With Autism Spectrum Disorders

Filed under science neuroscience brain psychology autism ASD research

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Britain’s first bionic veteran has a new brain-controlled robotic arm that is transforming his life.Andrew Garthwaite, 25, had his right arm blown clean off by a rocket-propelled grenade during a firefight with the Taliban in Afghanistan in September 2010. In January he had the state-of-the-art limb wired to his nervous system during a six-hour operation in Vienna, Austria.
Now he is getting to grips with his new body part and is able to ride his motorcycle and drive a car again. Mr Gathwaite, who lives with his new wife Kailey, also 25, in South Shields, Tyneside, said: 'It's been incredible. I thought I might never be the same. But my life is starting to get back to normal - I'm on my motorbike and I'm back in a car. I can do things that I never thought I would have been able to do'.

Britain’s first bionic veteran has a new brain-controlled robotic arm that is transforming his life.

Andrew Garthwaite, 25, had his right arm blown clean off by a rocket-propelled grenade during a firefight with the Taliban in Afghanistan in September 2010. In January he had the state-of-the-art limb wired to his nervous system during a six-hour operation in Vienna, Austria.

Now he is getting to grips with his new body part and is able to ride his motorcycle and drive a car again. Mr Gathwaite, who lives with his new wife Kailey, also 25, in South Shields, Tyneside, said:

'It's been incredible. I thought I might never be the same. But my life is starting to get back to normal - I'm on my motorbike and I'm back in a car. I can do things that I never thought I would have been able to do'.

Filed under bionic arm bionic implants brain neuroscience prosthetics robotics science technology nervous system

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Harvard scientists have created a type of cyborg tissue by embedding a three-dimensional network of functional, biocompatible, nanoscale wires into engineered human tissues.

The research addresses a concern that has long been associated with work on bioengineered tissue: how to create systems capable of sensing chemical or electrical changes in the tissue after it has been grown and implanted. The system might also represent a solution to researchers’ struggles in developing methods to directly stimulate engineered tissues and measure cellular reactions.
The process of building the networks is similar to that used to etch microchips. Beginning with a two-dimensional substrate, researchers laid out a mesh of organic polymer around nanoscale wires, which serve as the critical sensing elements. Nanoscale electrodes, which connect the nanowire elements, were then built within the mesh to enable nanowire transistors to measure the activity in cells without damaging them. Once completed, the substrate is then dissolved, leaving researchers with a netlike sponge, or a mesh, that can be folded or rolled into a host of three-dimensional shapes. Finally, the networks are porous enough to allow seeding them with cells and encourage those cells to grow in 3-D cultures.
Using heart and nerve cells, the Harvard research team successfully engineered tissues containing embedded nanoscale networks without affecting the cells’ viability or activity. Using the embedded devices, the researchers were then able to detect electrical signals generated by cells deep within the tissue, and to measure changes in those signals in response to cardio- or neuro-stimulating drugs.

Harvard scientists have created a type of cyborg tissue by embedding a three-dimensional network of functional, biocompatible, nanoscale wires into engineered human tissues.

The research addresses a concern that has long been associated with work on bioengineered tissue: how to create systems capable of sensing chemical or electrical changes in the tissue after it has been grown and implanted. The system might also represent a solution to researchers’ struggles in developing methods to directly stimulate engineered tissues and measure cellular reactions.

The process of building the networks is similar to that used to etch microchips. Beginning with a two-dimensional substrate, researchers laid out a mesh of organic polymer around nanoscale wires, which serve as the critical sensing elements. Nanoscale electrodes, which connect the nanowire elements, were then built within the mesh to enable nanowire transistors to measure the activity in cells without damaging them. Once completed, the substrate is then dissolved, leaving researchers with a netlike sponge, or a mesh, that can be folded or rolled into a host of three-dimensional shapes. Finally, the networks are porous enough to allow seeding them with cells and encourage those cells to grow in 3-D cultures.

Using heart and nerve cells, the Harvard research team successfully engineered tissues containing embedded nanoscale networks without affecting the cells’ viability or activity. Using the embedded devices, the researchers were then able to detect electrical signals generated by cells deep within the tissue, and to measure changes in those signals in response to cardio- or neuro-stimulating drugs.

Filed under artificial tissue neuroscience robotics science tissue technology medical implants nanoscale networks

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Behavioral test shows promise in predicting future problems with alcohol
By administering a simple behavioral test, Yale researchers were able to predict which mice would later exhibit alcoholism-related behaviors such as the inability to stop seeking alcohol and a tendency to relapse, the scientists report in the Aug. 26 issue of the journal Nature Neuroscience.
"We are trying to understand the neurobiology underlying familial risk for alcoholism," said Jane Taylor, the Charles B.G. Murphy Professor of Psychiatry and professor of psychology at the Yale School of Medicine and senior author of the study. "What is encouraging about this study is that we have identified both a behavioral indicator and a molecule that explains that risk."

Behavioral test shows promise in predicting future problems with alcohol

By administering a simple behavioral test, Yale researchers were able to predict which mice would later exhibit alcoholism-related behaviors such as the inability to stop seeking alcohol and a tendency to relapse, the scientists report in the Aug. 26 issue of the journal Nature Neuroscience.

"We are trying to understand the neurobiology underlying familial risk for alcoholism," said Jane Taylor, the Charles B.G. Murphy Professor of Psychiatry and professor of psychology at the Yale School of Medicine and senior author of the study. "What is encouraging about this study is that we have identified both a behavioral indicator and a molecule that explains that risk."

Filed under alcohol behavior brain neuroscience psychology science alcoholism

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