A novel function for p27 protein in the control of interneuron migration in the developing cerebral cortex

These results by GIGA-Neurosciences researchers (University of Liège, Belgium) increase our understanding of the mechanisms that drive neuronal migration in the cerebral cortex. Disruption of neuronal migration is associated with various neurological disorders characterized by mental retardation, epilepsy,  learning disabilities, or autism.

In a study published in Developmental Cell, the group of Laurent Nguyen, Research Associate of the FRS-FNRS and WELBIO investigator at GIGA-Neurosciences (University of Liège) has discovered a novel function for p27 in the control of interneuron migration in the developing cerebral cortex.