Neuroscientists watch imagination happening in the brain

“You may say I’m a dreamer, but I’m not the only one,” sang John Lennon in his 1971 song Imagine.

And thanks to the dreams of a BYU student, we now know more about where and how imagination happens in our brains.

Stefania Ashby and her faculty mentor devised experiments using MRI technology that would help them distinguish pure imagination from related processes like remembering.

“I was thinking a lot about planning for my own future and imagining myself in the future, and I started wondering how memory and imagination work together,” Ashby said. “I wondered if they were separate or if imagination is just taking past memories and combining them in different ways to form something I’ve never experienced before.”

There’s a bit of scientific debate over whether memory and imagination truly are distinct processes. So Ashby and her faculty mentor devised MRI experiments to put it to the test.

They asked study participants to provide 60 personal photographs for the “remember” section of the experiment. Participants also filled out a questionnaire beforehand to determine which scenarios would be unfamiliar to them and thus a better fit for the “imagine” section.

The researchers then showed people their own photographs during an MRI session to elicit brain activity that is strictly memory-based. A statistical analysis revealed distinctive patterns for memory and imagination.

“We were able to see the distinctions even in those small regions of the hippocampus,” Ashby said. “It’s really neat that we can see the difference between those two tasks in that small of a brain region.”

Ashby co-authored the study with BYU psychology and neuroscience professor Brock Kirwan for the journal Cognitive Neuroscience. Kirwan studies memory at Brigham Young University, and Ashby is one of many students that he has mentored.

“Stefania came in really excited about this project, she pitched it to me, and basically sold it to me right there,” Kirwan said. “It was really cool because it gave me a chance to become more immersed and really broaden my horizons.”

Stefania graduated in 2011 and is currently working as a research associate at UC Davis, where she uses neuroimaging to study individuals at risk of psychotic disorders such as schizophrenia. Her plan is to earn a Ph.D. in neuroscience and continue researching.

Image: Eleven areas of the brain are showing differential activity levels in a Dartmouth study using functional MRI to measure how humans manipulate mental imagery. Credited to Alex Schlegel, Dartmouth College

Researchers discover how and where imagination occurs in human brains

New insights into ‘mental workspace’ may help advance artificial intelligence

Philosophers and scientists have long puzzled over where human imagination comes from. In other words, what makes humans able to create art, invent tools, think scientifically and perform other incredibly diverse behaviors?

The answer, Dartmouth researchers conclude in a new study, lies in a widespread neural network — the brain’s “mental workspace” — that consciously manipulates images, symbols, ideas and theories and gives humans the laser-like mental focus needed to solve complex problems and come up with new ideas.

Their findings, titled “Network structure and dynamics of the mental workspace,” appear the week of Sept. 16 in the Proceedings of the National Academy of Sciences.

"Our findings move us closer to understanding how the organization of our brains sets us apart from other species and provides such a rich internal playground for us to think freely and creatively," says lead author Alex Schlegel, a graduate student in the Department of Psychological and Brain Sciences. "Understanding these differences will give us insight into where human creativity comes from and possibly allow us to recreate those same creative processes in machines."

Scholars theorize that human imagination requires a widespread neural network in the brain, but evidence for such a “mental workspace” has been difficult to produce with techniques that mainly study brain activity in isolation. Dartmouth researchers addressed the issue by asking: How does the brain allow us to manipulate mental imagery? For instance, imagining a bumblebee with the head of a bull, a seemingly effortless task but one that requires the brain to construct a totally new image and make it appear in our mind’s eye.

In the study, 15 participants were asked to imagine specific abstract visual shapes and then to mentally combine them into new more complex figures or to mentally dismantle them into their separate parts. Researchers measured the participants’ brain activity with functional MRI and found a cortical and subcortical network over a large part of the brain was responsible for their imagery manipulations. The network closely resembles the “mental workspace” that scholars have theorized might be responsible for much of human conscious experience and for the flexible cognitive abilities that humans have evolved.

The empathy machine

…Let’s dwell for a moment on ‘Silver Blaze’ (1892), Arthur Conan Doyle’s story of the gallant racehorse who disappeared, and his trainer who was found dead, just days before a big race. The hapless police are stumped, and Sherlock Holmes is called in to save the day. And save the day he does — by putting himself in the position of both the dead trainer and the missing horse. Holmes speculates that the horse is ‘a very gregarious creature’. Surmising that, in the absence of its trainer, it would have been drawn to the nearest town, he finds horse tracks, and tells Watson which mental faculty led him there. ‘See the value of imagination… We imagined what might have happened, acted upon that supposition, and find ourselves justified.’

Holmes takes an imaginative leap, not only into another human mind, but into the mind of an animal. This perspective-taking, being able to see the world from the point of view of another, is one of the central elements of empathy, and Holmes raises it to the status of an art.

Usually, when we think of empathy, it evokes feelings of warmth and comfort, of being intrinsically an emotional phenomenon. But perhaps our very idea of empathy is flawed. The worth of empathy might lie as much in the ‘value of imagination’ that Holmes employs as it does in the mere feeling of vicarious emotion. Perhaps that cold rationalist Sherlock Holmes can help us reconsider our preconceptions about what empathy is and what it does.

Though the scientific literature on empathy is complex, a recent review in Nature Neuroscience by a team of researchers from Harvard and Columbia including Jamil Zaki and Kevin Ochsner has distilled the phenomenon into three central stages. The first stage is ‘experience sharing’, or feeling someone else’s emotions as if they were your own — scared when they are scared, happy when they are happy, and so on. The second stage is ‘mentalising’, or consciously considering those states and their sources, and trying to work through understanding them. The final stage is ‘prosocial concern’, or being motivated to act — wanting, for example, to reach out to someone in pain. However, you don’t need all three to experience empathy. Instead, you can view these as three points on an empathetic continuum: first, you feel; then, you feel and you understand; and finally, you feel, understand, and are compelled to act on your understanding. It seems that the defining thing here is the feeling that accompanies all those stages.

Full article

The Future of Memory: Remembering, Imagining, and the Brain

During the past few years, there has been a dramatic increase in research examining the role of memory in imagination and future thinking. This work has revealed striking similarities between remembering the past and imagining or simulating the future, including the finding that a common brain network underlies both memory and imagination. Here, we discuss a number of key points that have emerged during recent years, focusing in particular on the importance of distinguishing between temporal and nontemporal factors in analyses of memory and imagination, the nature of differences between remembering the past and imagining the future, the identification of component processes that comprise the default network supporting memory-based simulations, and the finding that this network can couple flexibly with other networks to support complex goal-directed simulations. This growing area of research has broadened our conception of memory by highlighting the many ways in which memory supports adaptive functioning.

Fantasy-Reality Confusion a Primary Cause of Childhood Nighttime Fears

From monsters under the bed to bogeymen in the closet, most children experience nighttime fears at some point in their development. And while most grow out of them without any professional intervention, others contend with persistent and extended periods of these fears, with a risk of developing anxiety problems later in life.

As part of a large-scale project on nighttime fears funded by the Israeli Science Foundation, Prof. Avi Sadeh of Tel Aviv University’s School of Psychological Sciences is exploring how these fears fit into the normal developmental process — and when they become a problem. Together with Dr. Jonathan Kushnir, who completed his Ph.D. studies in the field in Prof. Sadeh’s lab, MA student Tamar Zisenwine, and Ph.D. student Michal Kaplan, he discovered that a child’s ability to differentiate fact from fiction has a huge impact on overcoming terror of things that go bump in the night.

In their study, published in Child Psychiatry and Human Development, the researchers found that preschoolers with persistent nighttime fears were far less able to distinguish reality from fantasy compared to their peers. The research will help clinicians and parents alike to develop interventions that can better soothe fretful children, he says, noting that a strong imagination can ultimately be used to the child’s psychological advantage.