Posts tagged corpus callosum

Posts tagged corpus callosum
Kim Peek, The Real Rain Man
Kim Peek, who lent inspiration to the fictional character Raymond Babbitt—played by Dustin Hoffman—in the movie Rain Man, was a remarkable savant. A savant is an individual who—with little or no apparent effort—completes intellectual tasks that would be impossible for ordinary people to master.
Kim Peek’s special abilities started early, around the age of a year and a half. He could read both pages of an open book at once, one page with one eye and the other with the other eye. This style of reading continued until his dead in 2009. His reading comprehension was impressive. He would retain 98 percent of the information he read. Since he spent most of his days in the library with his dad, he quickly made it through thousands of books, encyclopedia and maps. He could read a thick book in an hour and remember just about anything in it. Because he could quickly absorb loads of information and recall it when necessary, his condition made him a living encyclopedia and a walking GPS. He could provide driving directions between almost any two cities in the world. He could also do calendar calculations (“which day was June 15, 1632?”) and remember old baseball scores and a vast amount of musical, historical and political facts. His memory abilities were astounding.
Unlike many individuals with savant syndrome, Kim Peek was not afflicted with autistic spectrum disorder. Though he was strongly introverted, he did not have difficulties with social understanding and communication. The main cause of his remarkable abilities seems to have been the lack of connections between his brain’s two hemispheres. An MRI scan revealed an absence of the corpus callosum, the anterior commissure and the hippocampal commissure, the parts of the neurological system that transfer information between hemispheres. In some sense Kim was a natural born split-brain patient.
The split brain: A tale of two halves
In the first months after her surgery, shopping for groceries was infuriating. Standing in the supermarket aisle, Vicki would look at an item on the shelf and know that she wanted to place it in her trolley — but she couldn’t. “I’d reach with my right for the thing I wanted, but the left would come in and they’d kind of fight,” she says. “Almost like repelling magnets.” Picking out food for the week was a two-, sometimes three-hour ordeal. Getting dressed posed a similar challenge: Vicki couldn’t reconcile what she wanted to put on with what her hands were doing. Sometimes she ended up wearing three outfits at once. “I’d have to dump all the clothes on the bed, catch my breath and start again.”
In one crucial way, however, Vicki was better than her pre-surgery self. She was no longer racked by epileptic seizures that were so severe they had made her life close to unbearable. She once collapsed onto the bar of an old-fashioned oven, burning and scarring her back. “I really just couldn’t function,” she says. When, in 1978, her neurologist told her about a radical but dangerous surgery that might help, she barely hesitated. If the worst were to happen, she knew that her parents would take care of her young daughter. “But of course I worried,” she says. “When you get your brain split, it doesn’t grow back together.”
In June 1979, in a procedure that lasted nearly 10 hours, doctors created a firebreak to contain Vicki’s seizures by slicing through her corpus callosum, the bundle of neuronal fibres connecting the two sides of her brain. This drastic procedure, called a corpus callosotomy, disconnects the two sides of the neocortex, the home of language, conscious thought and movement control. Vicki’s supermarket predicament was the consequence of a brain that behaved in some ways as if it were two separate minds.
After about a year, Vicki’s difficulties abated. “I could get things together,” she says. For the most part she was herself: slicing vegetables, tying her shoe laces, playing cards, even waterskiing.
But what Vicki could never have known was that her surgery would turn her into an accidental superstar of neuroscience. She is one of fewer than a dozen ‘split-brain’ patients, whose brains and behaviours have been subject to countless hours of experiments, hundreds of scientific papers, and references in just about every psychology textbook of the past generation. And now their numbers are dwindling.
Through studies of this group, neuroscientists now know that the healthy brain can look like two markedly different machines, cabled together and exchanging a torrent of data. But when the primary cable is severed, information — a word, an object, a picture — presented to one hemisphere goes unnoticed in the other. Michael Gazzaniga, a cognitive neuroscientist at the University of California, Santa Barbara, and the godfather of modern split-brain science, says that even after working with these patients for five decades, he still finds it thrilling to observe the disconnection effects first-hand. “You see a split-brain patient just doing a standard thing — you show him an image and he can’t say what it is. But he can pull that same object out of a grab-bag,” Gazzaniga says. “Your heart just races!”