Vajrayana Meditation Techniques Associated with Tibetan Buddhism Can Enhance Brain Performance

Contrary to popular belief, not all meditation techniques produce similar effects of body and mind. Indeed, a recent study by researchers from the National University of Singapore (NUS) has demonstrated for the first time that different types of Buddhist meditation – namely the Vajrayana and Theravada styles of meditation - elicit qualitatively different influences on human physiology and behaviour, producing arousal and relaxation responses respectively.

In particular, the NUS research team found that Vajrayana meditation, which is associated with Tibetan Buddhism, can lead to enhancements in cognitive performance.

The study by Associate Professor Maria Kozhevnikov and Dr Ido Amihai from the Department of Psychology at the NUS Faculty of Arts and Social Sciences was first published in the journal PLOS ONE in July 2014.

Vajrayana and Theravada meditation produce different physiological responses

Previous studies had defined meditation as a relaxation response and had attempted to categorise meditation as either involving focused or distributed attentional systems. Neither of these hypotheses received strong empirical support, and most of the studies focused on Theravada meditative practices.

Assoc Prof Kozhevnikov and Dr Amihai examined four different types of meditative practices: two types of Vajrayana meditations (Tibetan Buddhism) practices (Visualisation of self-generation-as-Deity and Rig-pa) and two types of Theravada practices (Shamatha and Vipassana). They collected electrocardiographic (EKG) and electroencephalographic (EEG) responses and also measured behavioural performance on cognitive tasks using a pool of experienced Theravada practitioners from Thailand and Nepal, as well as Vajrayana practitioners from Nepal.

They observed that physiological responses during the Theravada meditation differ significantly from those during the Vajrayana meditation. Theravada meditation produced enhanced parasympathetic activation (relaxation). In contrast, Vajrayana meditation did not show any evidence of parasympathetic activity but showed an activation of the sympathetic system (arousal).

The researchers had also observed an immediate dramatic increase in performance on cognitive tasks following only Vajrayana styles of meditation. They noted that such dramatic boost in attentional capacity is impossible during a state of relaxation. Their results show that Vajrayana and Theravada styles of meditation are based on different neurophysiological mechanisms, which give rise to either an arousal or relaxation response.

Applications of the research findings

The findings from the study showed that Vajrayana meditation can lead to dramatic enhancement in cognitive performance, suggesting that Vajrayana meditation could be especially useful in situations where it is important to perform at one’s best, such as during competition or states of urgency. On the other hand, Theravada styles of meditation are an excellent way to decrease stress, release tension, and promote deep relaxation.

Further research

After seeing that even a single session of Vajrayana meditation can lead to radical enhancements in brain performance, Assoc Prof Kozhevnikov and Dr Amihai will be investigating whether permanent changes could occur after long-term practice. The researchers are also looking at how non-practitioners can benefit from such meditative practices.

Assoc Prof Kozhevnikov said, “Vajrayana meditation typically requires years of practice, so we are also looking into whether it is also possible to acquire the beneficial effects of brain performance by practicing certain essential elements of the meditation. This would provide an effective and practical method for non-practitioners to quickly increase brain performance in times of need.”

Eating Baked or Broiled Fish Weekly Boosts Brain Health

Eating baked or broiled fish once a week is good for the brain, regardless of how much omega-3 fatty acid it contains, according to researchers at the University of Pittsburgh School of Medicine. The findings, published online recently in the American Journal of Preventive Medicine, add to growing evidence that lifestyle factors contribute to brain health later in life.

Scientists estimate that more than 80 million people will have dementia by 2040, which could become a substantial burden to families and drive up health care costs, noted senior investigator James T. Becker, Ph.D., professor of psychiatry, Pitt School of Medicine. Some studies have predicted that lifestyle changes such as a reduction in rates of physical inactivity, smoking and obesity could lead to fewer cases of Alzheimer’s disease and other conditions of cognitive impairment in the elderly. The anti-oxidant effect of omega-3 fatty acids, which are found in high amounts in fish, seeds and nuts, and certain oils, also have been associated with improved health, particularly brain health.

“Our study shows that people who ate a diet that included baked or broiled, but not fried, fish have larger brain volumes in regions associated with memory and cognition,” Dr. Becker said. “We did not find a relationship between omega-3 levels and these brain changes, which surprised us a little. It led us to conclude that we were tapping into a more general set of lifestyle factors that were affecting brain health of which diet is just one part.”

Lead investigator Cyrus Raji, M.D., Ph.D., who now is in radiology residency training at UCLA, and the research team analyzed data from 260 people who provided information on their dietary intake, had high-resolution brain MRI scans, and were cognitively normal at two time points during their participation in the Cardiovascular Health Study (CHS), a 10-year multicenter effort that began in 1989 to identify risk factors for heart disease in people over 65.

“The subset of CHS participants answered questionnaires about their eating habits, such as how much fish did they eat and how was it prepared,” Dr. Raji said. “Baked or broiled fish contains higher levels of omega-3s than fried fish because the fatty acids are destroyed in the high heat of frying, so we took that into consideration when we examined their brain scans.”

People who ate baked or broiled fish at least once a week had greater grey matter brain volumes in areas of the brain responsible for memory (4.3 percent) and cognition (14 percent) and were more likely to have a college education than those who didn’t eat fish regularly, the researchers found. But no association was found between the brain differences and blood levels of omega-3s.

“This suggests that lifestyle factors, in this case eating fish, rather than biological factors contribute to structural changes in the brain,” Dr. Becker noted. “A confluence of lifestyle factors likely are responsible for better brain health, and this reserve might prevent or delay cognitive problems that can develop later in life.”

How does the cerebellum work?

Nothing says “don’t mess with me” like a deeply-fissured cortex. Even the sharpest jaws and claws in the animal kingdom are worthless without some serious thought muscle under the hood. But beneath the highly convoluted membrane covering the brains of the evolutionary upper crust hides the original crumpled processor—the cerebellum. How this organ might actually work is the subject of a review published in Frontiers of Systems Neuroscience by researchers at the University of Minnesota.

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Study shows puzzle games can improve mental flexibility

A recent study by Nanyang Technological University (NTU) scientists showed that adults who played the physics-based puzzle video game Cut the Rope regularly, for as little as an hour a day, had improved executive functions.

The executive functions in your brain are important for making decisions in everyday life when you have to deal with sudden changes in your environment – better known as thinking on your feet. An example would be when the traffic light turns amber and a driver has to decide in an instant if he will be able to brake in time or if it is safer to travel across the junction/intersection.

The video game study by Assistant Professor Michael D. Patterson and his PhD student Mr Adam Oei, tested four different games for the mobile platform, as their previous research had shown that different games trained different skills.

The games varied in their genres, which included a first person shooter (Modern Combat); arcade (Fruit Ninja); real-time strategy (StarFront Collision); and a complex puzzle (Cut the Rope).

NTU undergraduates, who were non-gamers, were then selected to play an hour a day, 5 days a week on their iPhone or iPod Touch. This video game training lasted for 4 weeks, a total of 20 hours.

Prof Patterson said students who played Cut the Rope, showed significant improvement on executive function tasks while no significant improvements were observed in those playing the other three games.

“This finding is important because previously, no video games have demonstrated this type of broad improvement to executive functions, which are important for general intelligence, dealing with new situations and managing multitasking,” said Prof Patterson, an expert in the psychology of video games.

“This indicates that while some games may help to improve mental abilities, not all games give you the same effect. To improve the specific ability you are looking for, you need to play the right game,” added Mr Oei.

The abilities tested in this study included how fast the players can switch tasks (an indicator of mental flexibility); how fast can the players adapt to a new situation instead of relying on the same strategy (the ability to inhibit prepotent or predominant responses); and how well they can focus on information while blocking out distractors or inappropriate responses (also known as the Flanker task in cognitive psychology).

Prof Patterson said the reason Cut the Rope improved executive function in their players was probably due to the game’s unique puzzle design. Strategies which worked for earlier levels would not work in later levels, and regularly forced the players to think creatively and try alternate solutions. This is unlike most other video games which keep the same general mechanics and goals, and just speed up or increase the number of items to keep track of. 

After 20 hours of game play, players of Cut the Rope could switch between tasks 33 per cent faster, were 30 per cent faster in adapting to new situations, and 60 per cent better in blocking out distractions and focusing on the tasks at hand than before training.

All three tests were done one week after the 52 students had finished playing their assigned game, to ensure that these were not temporary gains due to motivation or arousal effects.

The study will be published in the academic journal, Computers in Human Behavior, this August, but is available currently online. This is the first study that showed broad transfer to several different executive functions, further providing evidence the video games can be effective in training human cognition.

“This result could have implications in many areas such as educational, occupational and rehabilitative settings,” Prof Patterson said.

“In future, with more studies, we will be able to know what type of games improves specific abilities, and prescribe games that will benefit people aside from just being entertainment.”

In their previous study published last year in PloS One, a top academic journal, Prof Patterson and Mr Oei studied the effects mobile gaming had on 75 NTU undergraduates.

The non-gamers were instructed to play one of the following games: “match three” game Bejeweled, virtual life simulation game The Sims, and action shooter Modern Combat.

The study findings showed that adults who play action games improved their ability to track multiple objects in a short span of time, useful when driving during a busy rush hour; while other games improved the participants’ ability for visual search tasks, useful when picking out an item from a large supermarket.

Moving forward, the Prof Patterson is keen to look at whether there is any improvement from playing such games in experienced adult gamers and how much improvement one can make through playing games.

Researchers publish one of the longest longitudinal studies of cognition in MS

Researchers at Kessler Foundation and the Cleveland Clinic have published one of the longest longitudinal studies of cognition in multiple sclerosis (MS). The article, “Cognitive impairment in multiple sclerosis: An 18-year follow-up study,” was epublished by Multiple Sclerosis and Related Disorders on April 13, 2014. Results provide insight into the natural evolution of cognitive changes over time, an important consideration for researchers and clinicians. Authors are Lauren B. Strober, PhD, of Kessler Foundation and  Stephen M. Rao, PhD, Jar-Chi Lee, Elizabeth Fisher, PhD, and Richard Rudick, MD, of the Cleveland Clinic.

“While cognitive impairment is known to affect 40 to 65% of individuals with MS, few studies have followed the pattern of cognitive decline over time, which is important for understanding long-term care and outcomes associated with MS,” said Dr. Strober, senior research scientist at Kessler Foundation. “Our study was based on a unique sample of 22 patients who underwent neuropsychological testing at entry into the original phase 3 clinical trial of intramuscular interferon beta-1a, and again at 18-year followup.”

At baseline, 9 patients (41%) had cognitive impairment; at 18-year followup, 13 patients (59%), were found to be impaired. Significant declines over time were found in information processing speed, auditory attention, memory, episodic learning and visual construction. Decline was steeper in the unimpaired than in the impaired group, as indicated by the Symbol Digit Modalities Test (SDMT).

"These longitudinal data contribute substantially to our knowledge of the course of cognitive decline in MS,” noted John DeLuca, PhD, VP of Research & Training at Kessler Foundation. “In light of the young age at diagnosis, this perspective is fundamental to the development of rehabilitation strategies that meet the needs of people dealing with the cognitive effects of MS.”

The study was funded by Biogen Idec.

Brain imaging shows enhanced executive brain function in people with musical training

A controlled study using functional MRI brain imaging reveals a possible biological link between early musical training and improved executive functioning in both children and adults, report researchers at Boston Children’s Hospital. The study, appearing online June 17 in the journal PLOS ONE, uses functional MRI of brain areas associated with executive function, adjusting for socioeconomic factors.

Executive functions are the high-level cognitive processes that enable people to quickly process and retain information, regulate their behaviors, make good choices, solve problems, plan and adjust to changing mental demands.

"Since executive functioning is a strong predictor of academic achievement, even more than IQ, we think our findings have strong educational implications," says study senior investigator Nadine Gaab, PhD, of the Laboratories of Cognitive Neuroscience at Boston Children’s. "While many schools are cutting music programs and spending more and more time on test preparation, our findings suggest that musical training may actually help to set up children for a better academic future."

While it’s already clear that musical training relates to cognitive abilities, few previous studies have looked at its effects on executive functions specifically. Among these studies, results have been mixed and limited by a lack of objective brain measurements, examination of only a few aspects of executive function, lack of well-defined musical training and control groups, and inadequate adjustment for factors like socioeconomic status.

Gaab and colleagues compared 15 musically trained children, 9 to 12, with a control group of 12 untrained children of the same age. Musically trained children had to have played an instrument for at least two years in regular private music lessons. (On average, the children had played for 5.2 years and practiced 3.7 hours per week, starting at the age of 5.9.) The researchers similarly compared 15 adults who were active professional musicians with 15 non-musicians. Both control groups had no musical training beyond general school requirements.

Since family demographic factors can influence whether a child gets private music lessons, the researchers matched the musician/non-musician groups for parental education, job status (parental or their own) and family income. The groups, also matched for IQ, underwent a battery of cognitive tests, and the children also had functional MRI imaging (fMRI) of their brains during testing.

On cognitive testing, adult musicians and musically trained children showed enhanced performance on several aspects of executive functioning. On fMRI, the children with musical training showed enhanced activation of specific areas of the prefrontal cortex during a test that made them switch between mental tasks. These areas, the supplementary motor area, the pre-supplementary area and the right ventrolateral prefrontal cortex, are known to be linked to executive function.

"Our results may also have implications for children and adults who are struggling with executive functioning, such as children with ADHD or [the] elderly," says Gaab. "Future studies have to determine whether music may be utilized as a therapeutic intervention tools for these children and adults."

The researchers note that children who study music may already have executive functioning abilities that somehow attract them to music and predispose them to stick with their lessons. To establish that musical training influences executive function, and not the other way around, they hope to perform additional studies that follow children over time, assigning them to musical training at random.

Brain signals link physical fitness to better language skills in children

Children who are physically fit have faster and more robust neuro-electrical brain responses during reading than their less-fit peers, researchers report.

These differences correspond with better language skills in the children who are more fit, and occur whether they’re reading straightforward sentences or sentences that contain errors of grammar or syntax.

The new findings, reported in the journal Brain and Cognition, do not prove that higher fitness directly influences the changes seen in the electrical activity of the brain, the researchers say, but offer a potential mechanism to explain why fitness correlates so closely with better cognitive performance on a variety of tasks.

“All we know is there is something different about higher and lower fit kids,” said University of Illinois kinesiology and community health professor Charles Hillman who led the research with graduate student Mark Scudder and psychology professor Kara Federmeier. “Now whether that difference is caused by fitness or maybe some third variable that (affects) both fitness and language processing, we don’t know yet.”

The researchers used electroencephalography (EEG), placing an electrode cap on the scalp to capture some of the electrical impulses associated with brain activity. The squiggly readouts from the electrodes look like seismic readings captured during an earthquake, and characteristic wave patterns are associated with different tasks.

These patterns are called “event-related potentials” (ERPs), and vary according to the person being evaluated and the nature of the stimulus, Scudder said.

For example, if you hear or read a word in a sentence that makes sense (“You wear shoes on your feet”), the component of the brain waveform known as the N400 is less pronounced than if you read a sentence in which the word no longer makes sense (“At school we sing shoes and dance,” for example), Scudder said.

“We focused on the N400 because it is associated with the processing of the meaning of a word,” he said. “And then we also looked at another ERP, the P600, which is associated with the grammatical rules of a sentence.” Federmeier, a study co-author, is an expert in the neurobiological basis of language. Her work inspired the new analysis.

The researchers found that children who were more fit (as measured by oxygen uptake during exercise) had higher amplitude N400 and P600 waves than their less-fit peers when reading normal or nonsensical sentences. The N400 also had shorter latency in children who were more fit, suggesting that they processed the same information more quickly than their peers.

Most importantly, the researchers said, these differences in brain activity corresponded to better reading performance and language comprehension in the children who were more fit.

“Previous reports have shown that greater N400 amplitude is seen in higher-ability readers,” Scudder said.

“Our study shows that the brain function of higher fit kids is different, in the sense that they appear to be able to better allocate resources in the brain towards aspects of cognition that support reading comprehension,” Hillman said.

More work must be done to tease out the causes of improved cognition in kids who are more fit, Hillman said, but the new findings add to a growing body of research that finds strong links between fitness and healthy brain function.

Many studies conducted in the last decade, on children and older adults, ”have repeatedly demonstrated an effect of increases in either physical activity in one’s lifestyle or improvements in aerobic fitness, and the implications of those health behaviors for brain structure, brain function and cognitive performance,” Hillman said.