Neuroscience

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Posts tagged brain

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A new study by researchers at UT Dallas and the University of Michigan has found that the strength of communication between the left and right hemispheres of the brain predicts performance on basic arithmetic problems.  The findings shed light on the neural basis of human math abilities and suggest a possible route to aiding those who suffer from dyscalculia— an inability to understand and manipulate numbers.
It has been known for some time that the parietal cortex, the top/middle region of the brain, plays a central role in so-called numerical cognition—our ability to process numerical information. Previous brain imaging studies have shown that the right parietal region is primarily involved in basic quantity processing (like gauging relative amounts of fruit in baskets), while the left parietal region is involved in more precise numerical operations like addition and subtraction. What has not been known is whether the two hemispheres can work together to improve math performance. The new study demonstrates that they can. The findings were recently published online in Cerebral Cortex.

A new study by researchers at UT Dallas and the University of Michigan has found that the strength of communication between the left and right hemispheres of the brain predicts performance on basic arithmetic problems.  The findings shed light on the neural basis of human math abilities and suggest a possible route to aiding those who suffer from dyscalculia— an inability to understand and manipulate numbers.

It has been known for some time that the parietal cortex, the top/middle region of the brain, plays a central role in so-called numerical cognition—our ability to process numerical information. Previous brain imaging studies have shown that the right parietal region is primarily involved in basic quantity processing (like gauging relative amounts of fruit in baskets), while the left parietal region is involved in more precise numerical operations like addition and subtraction. What has not been known is whether the two hemispheres can work together to improve math performance. The new study demonstrates that they can. The findings were recently published online in Cerebral Cortex.

Filed under brain dyscalculia neuroscience psychology science numerical cognition math performance

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Tuning a piano also tunes the brain, say researchers who have seen structural changes within the brains of professional piano tuners.
Researchers at University College London and Newcastle University found listening to two notes played simultaneously makes the brain adapt. Brain scans revealed highly specific changes in the hippocampus, which governs memory and navigation. These correlated with the number of years tuners had been doing this job.
The Wellcome Trust researchers used magnetic resonance imaging to compare the brains of 19 professional piano tuners - who play two notes simultaneously to make them pitch-perfect - and 19 other people. What they saw was highly specific changes in both the grey matter - the nerve cells where information processing takes place - and the white matter - the nerve connections - within the brains of the piano tuners.
Investigator Sundeep Teki said: “We already know that musical training can correlate with structural changes, but our group of professionals offered a rare opportunity to examine the ability of the brain to adapt over time to a very specialised form of listening.”
Other researchers have noted similar hippocampal changes in taxi drivers as they build up detailed information needed to find their way around London’s labyrinth of streets. Prof Tim Griffiths, who led the latest study, published in Neuroscience, said: “There has been little work on the role of the hippocampus in auditory analysis. “Our study is consistent with a form of navigation in pitch space as opposed to the more accepted role in spatial navigation.”

Tuning a piano also tunes the brain, say researchers who have seen structural changes within the brains of professional piano tuners.

Researchers at University College London and Newcastle University found listening to two notes played simultaneously makes the brain adapt. Brain scans revealed highly specific changes in the hippocampus, which governs memory and navigation. These correlated with the number of years tuners had been doing this job.

The Wellcome Trust researchers used magnetic resonance imaging to compare the brains of 19 professional piano tuners - who play two notes simultaneously to make them pitch-perfect - and 19 other people. What they saw was highly specific changes in both the grey matter - the nerve cells where information processing takes place - and the white matter - the nerve connections - within the brains of the piano tuners.

Investigator Sundeep Teki said: “We already know that musical training can correlate with structural changes, but our group of professionals offered a rare opportunity to examine the ability of the brain to adapt over time to a very specialised form of listening.”

Other researchers have noted similar hippocampal changes in taxi drivers as they build up detailed information needed to find their way around London’s labyrinth of streets. Prof Tim Griffiths, who led the latest study, published in Neuroscience, said: “There has been little work on the role of the hippocampus in auditory analysis. “Our study is consistent with a form of navigation in pitch space as opposed to the more accepted role in spatial navigation.”

Filed under brain hippocampus music neuroscience psychology science auditory cortex

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Earphones ‘potentially as dangerous as noise from jet engines,’ according to new University of Leicester study: New research identifies for the first time how high volumes of sound damage nerve cell coating leading to temporary deafness.
University of Leicester researcher Dr Martine Hamann of the Department of Cell Physiology and Pharmacology, who led the study, said:

"The research allows us to understand the pathway from exposure to loud noises to hearing loss. Dissecting the cellular mechanisms underlying this condition is likely to bring a very significant healthcare benefit to a wide population. The work will help prevention as well as progression into finding appropriate cures for hearing loss.”

Earphones ‘potentially as dangerous as noise from jet engines,’ according to new University of Leicester study: New research identifies for the first time how high volumes of sound damage nerve cell coating leading to temporary deafness.

University of Leicester researcher Dr Martine Hamann of the Department of Cell Physiology and Pharmacology, who led the study, said:

"The research allows us to understand the pathway from exposure to loud noises to hearing loss. Dissecting the cellular mechanisms underlying this condition is likely to bring a very significant healthcare benefit to a wide population. The work will help prevention as well as progression into finding appropriate cures for hearing loss.”

Filed under science neuroscience hearing psychology brain hearing loss

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One biotech startup wants to restore vision in blind patients with a gene therapy that gives light sensitivity to neurons that don’t normally possess it.
The attempt, by Ann Arbor, Michigan-based Retrosense Therapeutics, will use so-called optogenetics. Scientists have used the technique over the last few years as a research tool to study brain circuits and the neural control of behavior by directing neuron activity with flashes of light. But Retrosense and others groups are pushing to bring the technique to patients in clinical trials.
The idea behind Retrosense’s experimental therapy is to use optogenetics to treat patients who have lost their vision due to retinal degenerative diseases such as retinitis pigmentosa. Patients with retinitis pigmentosa experience progressive and irreversible vision loss because the rods and cones of their eyes die due to an inherited condition. If the company is successful, the treatment could also help patients with the most common form of macular degeneration, which affects nearly a million people in the United States. The U.S. Food and Drug Administration hasn’t approved any therapies for either condition.

One biotech startup wants to restore vision in blind patients with a gene therapy that gives light sensitivity to neurons that don’t normally possess it.

The attempt, by Ann Arbor, Michigan-based Retrosense Therapeutics, will use so-called optogenetics. Scientists have used the technique over the last few years as a research tool to study brain circuits and the neural control of behavior by directing neuron activity with flashes of light. But Retrosense and others groups are pushing to bring the technique to patients in clinical trials.

The idea behind Retrosense’s experimental therapy is to use optogenetics to treat patients who have lost their vision due to retinal degenerative diseases such as retinitis pigmentosa. Patients with retinitis pigmentosa experience progressive and irreversible vision loss because the rods and cones of their eyes die due to an inherited condition. If the company is successful, the treatment could also help patients with the most common form of macular degeneration, which affects nearly a million people in the United States. The U.S. Food and Drug Administration hasn’t approved any therapies for either condition.

Filed under science vision neuroscience brain optogenetics genetics neuron

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A bionic eye has given an Australian woman partial sight and researchers say it is an important step towards eventually helping visually impaired people get around independently.
Dianne Ashworth, who has severe vision loss due to the inherited condition retinitis pigmentosa, was fitted with a prototype bionic eye in May at the Royal Victorian Eye and Ear Hospital.
"It was really funny when it switched on I was waiting, waiting … I had these goggles on and I didn’t know what to expect, and I don’t know if anyone did know what I was going to see … Then all of a sudden I went ‘yep’ I could see a little flash and it was like a little, I suppose, a splinter … There were different shapes and dark black, lines of dark black and white lines together … Then that turned into splotches of black with white around them and cloud-like images … I can remember when the first bigger image came I just went ‘Wow,’ because I just didn’t expect it at all but it was amazing," she said.The bionic eye, designed, built and tested by the Bionic Vision Australia, a consortium of researchers partially funded by the Australian government, is equipped with 24 electrodes with a small wire that extends from the back of the eye to a receptor attached behind the ear.

A bionic eye has given an Australian woman partial sight and researchers say it is an important step towards eventually helping visually impaired people get around independently.

Dianne Ashworth, who has severe vision loss due to the inherited condition retinitis pigmentosa, was fitted with a prototype bionic eye in May at the Royal Victorian Eye and Ear Hospital.

"It was really funny when it switched on I was waiting, waiting … I had these goggles on and I didn’t know what to expect, and I don’t know if anyone did know what I was going to see … Then all of a sudden I went ‘yep’ I could see a little flash and it was like a little, I suppose, a splinter … There were different shapes and dark black, lines of dark black and white lines together … Then that turned into splotches of black with white around them and cloud-like images … I can remember when the first bigger image came I just went ‘Wow,’ because I just didn’t expect it at all but it was amazing," she said.

The bionic eye, designed, built and tested by the Bionic Vision Australia, a consortium of researchers partially funded by the Australian government, is equipped with 24 electrodes with a small wire that extends from the back of the eye to a receptor attached behind the ear.

Filed under science neuroscience technology vision bionic implants bionic eye robotics brain

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Pretend play can be fun for preschool children, but a new University of Virginia study, published in the current online edition of the journal Psychological Bulletin, finds that it is not as crucial to a child’s development as currently believed. Pretend play is any play a child engages in, alone, with playmates, or with adults, that involves uses of the imagination to create a fantasy world or situation, such as making toy cars go “vrrooooom” or making dolls talk.
Much of the previously presented “evidence” for the vitality of pretend play to development is derived from flawed methodology, according to Angeline Lillard, the new study’s lead author and a U.Va. professor of psychology in the College of Arts & Sciences. She said testers might have been biased by knowledge that they were testing children who had engaged in adult-directed pretend play prior to testing.
"We found no good evidence that pretend play contributes to creativity, intelligence or problem-solving," Lillard said. "However, we did find evidence that it just might be a factor contributing to language, storytelling, social development and self-regulation."

Pretend play can be fun for preschool children, but a new University of Virginia study, published in the current online edition of the journal Psychological Bulletin, finds that it is not as crucial to a child’s development as currently believed. Pretend play is any play a child engages in, alone, with playmates, or with adults, that involves uses of the imagination to create a fantasy world or situation, such as making toy cars go “vrrooooom” or making dolls talk.

Much of the previously presented “evidence” for the vitality of pretend play to development is derived from flawed methodology, according to Angeline Lillard, the new study’s lead author and a U.Va. professor of psychology in the College of Arts & Sciences. She said testers might have been biased by knowledge that they were testing children who had engaged in adult-directed pretend play prior to testing.

"We found no good evidence that pretend play contributes to creativity, intelligence or problem-solving," Lillard said. "However, we did find evidence that it just might be a factor contributing to language, storytelling, social development and self-regulation."

Filed under brain development neuroscience psychology science pretend play

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If you start exercising, your brain recognizes this as a moment of stress. As your heart pressure increases, the brain thinks you are either fighting the enemy or fleeing from it. To protect yourself and your brain from stress, you release a protein called BDNF (Brain-Derived Neurotrophic Factor). This BDNF has a protective and also reparative element to your memory neurons and acts as a reset switch. That’s why we often feel so at ease and like things are clear after exercising.
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If you start exercising, your brain recognizes this as a moment of stress. As your heart pressure increases, the brain thinks you are either fighting the enemy or fleeing from it. To protect yourself and your brain from stress, you release a protein called BDNF (Brain-Derived Neurotrophic Factor). This BDNF has a protective and also reparative element to your memory neurons and acts as a reset switch. That’s why we often feel so at ease and like things are clear after exercising.

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Filed under science brain neuroscience exercise happiness endorphins psychology protein

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Robots hunt neurons to record brain activity

Devices could reveal inner workings of neurons and how they communicate with each other.

Automated assistance may soon be available to neuroscientists tackling the brain’s complex circuitry, according to research presented last week at the Aspen Brain Forum in Colorado. Robots that can find and simultaneously record the activity of dozens of neurons in live animals could help researchers to reveal how connected cells interpret signals from one another and transmit information across brain areas — a task that would be impossible using single-neuron studies.

A robot that can access the internal workings of neurons could be scaled up to allow 100 cells to be studied at a time. MIT McGovern Institute/E. Boyden/Sputnik Animation

The robots are designed to perform whole-cell patch-clamping, a difficult but powerful method that allows neuroscientists to access neurons’ internal electrical workings, says Edward Boyden of the Massachusetts Institute of Technology in Cambridge, who is leading the work.

Read more …

Filed under neuron science neuroscience brain robots robotics

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Boo! Robots learn to jump like frightened mammals

ROBOTS developed in the safety of a laboratory can be too slow to react to the dangers of the real world. But software inspired by biology promises to give robots the equivalent of the mammalian amygdala, a part of the brain that responds quickly to threats.

(Image: SuperStock)

STARTLE, developed by Mike Hook and colleagues at Roke Manor Research of Romsey in Hampshire, UK, employs an artificial neural network to look out for abnormal or inconsistent data. Once it has been taught what is out of the ordinary, it can recognise dangers in the environment.

For instance, from data fed by a robotic vehicle’s on-board sensors, STARTLE could notice a pothole and pass a warning to the vehicle’s control system to focus more computing resources on that part of the road.

"If it sees something anomalous then investigative processing is cued; this allows us to use computationally expensive algorithms only when needed for assessing possible threats, rather than responding equally to everything," says Hook.

This design mimics the amygdala, which provides a rapid response to threats. The amygdala helps small animals to deal with complex, fast-changing surroundings, allowing them to ignore most sensory stimuli. “The key is that it’s for spotting anomalous conditions,” says Hook, “not routine ones.”

STARTLE has been tested in both vehicle navigation and robot health monitoring. In the latter, it can be trained to respond to danger signs, such as sudden changes in battery power or temperature. It has also been tested in computer networks, as a way to detect security threats, having been trained to identify the pattern of activity associated with an attack.

"A robot amygdala network could be useful," says neuroscientist Keith Kendrick of the University of Electronic Science and Technology of China in Chengdu. "Such a low-resolution analysis will sometimes make mistakes, and you will avoid something needlessly." But a slower, high-resolution analysis is also carried out, he says, which can override the mistakes.

Hooks says that STARTLE could be useful for any robots in complex environments. For example, a robot vehicle would be able to spot other drivers behaving erratically, a major challenge for conventional computing.

Source: NewScientist

Filed under science neuroscience biology ANN AI neural networks brain psychology STARTLE

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Robots that can read and respond to brain waves will eventually help stroke patients regain movement, using new neural interfaces that can re-train damaged motor pathways. Neuroscientists have made great strides in brain-machine interfaces that can respond to a person’s thoughts — a new generation will drive a non-invasive robotic orthotic, retraining the patient’s own body.
Patients who have suffered a stroke or other injury can lose the active use of their limbs, rendering them unable to simply think about moving an arm or hand and then do it. Sometimes it’s possible to re-establish the lost connection, with time and repetitive physical therapy. Researchers at Rice University are using a robotic exoskeleton and a neural interface to improve matters.

Robots that can read and respond to brain waves will eventually help stroke patients regain movement, using new neural interfaces that can re-train damaged motor pathways. Neuroscientists have made great strides in brain-machine interfaces that can respond to a person’s thoughts — a new generation will drive a non-invasive robotic orthotic, retraining the patient’s own body.

Patients who have suffered a stroke or other injury can lose the active use of their limbs, rendering them unable to simply think about moving an arm or hand and then do it. Sometimes it’s possible to re-establish the lost connection, with time and repetitive physical therapy. Researchers at Rice University are using a robotic exoskeleton and a neural interface to improve matters.

Filed under brain brain injury neuroscience psychology robotics science stroke technology robots

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