The Obese Brain May Thwart Weight Loss

New research by Terry Davidson, director of American University’s Center for Behavioral Neuroscience, indicates that diets that lead to obesity—diets high in saturated fat and refined sugar—may cause changes to the brains of obese people that in turn may fuel overconsumption of those same foods and make weight loss more challenging.

“It is a vicious cycle that may explain why obesity is so difficult to overcome,” said Davidson, also a professor of psychology at AU.

Davidson recently published his research, “The Effects of a High-Energy Diet on Hippocampal-Dependent Discrimination Performance and Blood-Brain Barrier Integrity Differ for Diet-Induced Obese and Diet-Resistant Rats,” in the journal Physiology & Behavior.