By Matthew Hutson | July 30, 2012
Why we are biased toward things on our dominant side
Image: GETTY IMAGES
If you are right-handed, chances are you will make different choices than your left-handed friends. A series of recent studies shows that we associate our dominant side with good and our nondominant side with bad, preferring products and people that happen to be on our “good” side over those closer to the other half of our body.
The theory of embodied cognition, widely embraced by cognitive scientists in recent years, holds that our abstract ideas are grounded in our physical experiences in the world. (See above: “embraced,” “holds,” “grounded.”) Daniel Casasanto, a psychologist at the New School for Social Research, began to wonder: If our bodies shape our thinking, do people with different bodies think differently? He has been using handedness as a test bed for this body-specific hypothesis.
In a set of studies published in 2009 Casasanto found that right-handers associate right with good and left with bad and that left-handers make the reverse associations. People prefer objects, job candidates and images of alien creatures on their dominant side to those on their nondominant side. In 2010 he reported that presidential candidates (Kerry, Bush, Obama and McCain) gesture with their dominant hands when making positive points and their weak hands to emphasize darker matters. And he has collected data to suggest that lefties hold higher opinions of their flight attendants when seated on the right side of a plane.
To rule out the possibility that this bias is purely genetic, like handedness is, Casasanto handicapped people’s preferred hands. In a 2011 study he had subjects manipulate dominoes while wearing a bulky ski glove on their good hand. Afterward, they showed a bias against things on that side. The results suggest that we look kindly on half the world because we can interact with that side fluently. Make it a hassle, and opinions flip.
Most recently, Casasanto reported in January in Cognitive Science that children as young as six display a handedness bias. Kids were asked which animal in a series of cartoon pairs looked nicer or smarter. The right-handers more often chose the drawing on the right side, and the left-handers more often chose the animal on the left. They also elected to put away their preferred toys in boxes on their dominant side.
“We all walk around with these lopsided bodies and have to interact with our environment in systematically different ways,” Casasanto notes. Given how broadly those interactions can influence our thinking, he says, “body specificity may be shaping our judgments in the real world in ways that we never suspected.”
Source: Scientific American
Filed under science neuroscience brain psychology cognition dominant side right-handers left-handers preferences
When rules change, brain falters
For the human brain, learning a new task when rules change can be a surprisingly difficult process marred by repeated mistakes, according to a new study by Michigan State University psychology researchers.
Imagine traveling to Ireland and suddenly having to drive on the left side of the road. The brain, trained for right-side driving, becomes overburdened trying to suppress the old rules while simultaneously focusing on the new rules, said Hans Schroder, primary researcher on the study.
Filed under brain learning neuroscience psychology science research
Neuroscientist keeps astronauts awake with ISS lighting tweaks
A neuroscientist is working with Nasa to develop special lamps that could help restore the circadian rhythm of exhausted astronauts working aboard the International Space Station (ISS).
Thomas Jefferson University neuroscientist George C Brainard, who has headed up the university’s Light Research Program since 1984, received approval for the lights in early 2012 and 100 of the LED models are due to be sent to Nasa by mid-2015. The lights have three different colour temperatures to help ease the astronauts into morning, nighttime and normal working mode.
"An astronaut here on Earth experiences a 24-hour day/night cycle just like you and I," explained Brainard. "Now when they’re on the space station, they’re circling the planet every 90 minutes. So they’ve gone from a 24-hour day to a 90-minute day."
Filed under LED bulbs NASA circadian rhythms mood neuroscience performance science sleep space astronauts
July 30, 2012
(Medical Xpress) — A new study by researchers at the Menzies Research Institute Tasmania (Menzies) suggests that one of the main treatments for multiple sclerosis (MS) may also increase the amount of vitamin D patients receive from sun exposure.
More people suffer with MS per capita in Tasmania than in any other state in Australia. There is currently no cure, but treatments are available to ease some of the symptoms.
This observational study published in the prestigious journal Neurology found that patients taking one of the most common treatments for MS, interferon-beta, had higher vitamin D levels than those not on this treatment or those using other forms of treatment for MS.
Around 60 per cent of MS patients with the relapsing-remitting form of MS are treated with interferon-beta. It is derived from a naturally-occurring component of the human immune system and has been found to reduce the frequency of relapse and other specific symptoms of MS.
Despite being a front-line treatment in MS, how interferon-beta actually works in MS is unclear, though it is thought to act by affecting the immune system.
The study used data from the MS Longitudinal Study, from 2002-2005, and this analysis used data from 178 persons with MS living in southern Tasmania.
Menzies researchers Dr. Niall Stewart and Dr. Steve Simpson, Jr. were co-first authors on the paper. Dr. Simpson says the findings suggest that part of the therapeutic effects of interferon-beta on relapse in MS may be through its effects on vitamin D, since vitamin D has the ability to reduce inflammatory pathways in the immune system.
“Not only did we find that persons taking interferon-beta had higher vitamin D levels than those not taking it, we also found that this increase in vitamin D was due to an enhancement of the association between sun and vitamin D, with persons on interferon-beta having nearly three-times as much vitamin D from similar amounts of sun exposure to those not taking interferon-beta,” Dr. Simpson said.
“We have previously shown persons with MS with higher vitamin D levels had lower numbers of relapses. In this analysis, however, we found that vitamin D was only associated with reduced risk of relapse among those using interferon-beta.
“Interestingly, the reciprocal was also true, with interferon-beta only associated with reduced risk of relapse among those with higher levels of vitamin D,” Dr. Simpson said.
Senior author, Professor Bruce Taylor, says the new findings have the potential to markedly affect clinical practice in the treatment of MS, but cautions that more research is required.
“This study adds to the growing body of research into MS, but before we can apply these findings to MS treatment practice, clinical trials must be done to prove these associations. Menzies is planning to undertake such a trial in the future,” Professor Taylor said.
“This study does provide further support for persons with MS to periodically have their vitamin D measured, particularly in winter, and if they are deficient, to seek the advice of their physician as to whether supplementation is appropriate for them.”
Provided by University of Tasmania
Source: medicalxpress.com
Filed under science neuroscience MS psychology vitamin D sun exposure
A better judge of character with oxytocin nasal spray?
In other contexts, oxytocin is already well-known as the “bliss hormone”. The hormone is secreted upon stimulation by touch and is known to result in a feeling of calm and physical relaxation. It is also used to induce labour in childbirth and as an aid for women experiencing difficulties in breastfeeding.
Oxytocin has also been referred to as a “mindreading” hormone. Recent research findings show that there may be some truth to these claims – although the mindreading component may have a more down-to-earth explanation.
Filed under science neuroscience brain psychology oxytocin research mind reading bliss hormone facial expression emotions addiction mental health
Smell the potassium: Surprising find in study of sex- and aggression-triggering vomeronasal organ
"We found two new ion channels—both of them potassium channels—through which VNO neurons are activated in mice," says Associate Investigator C. Ron Yu, Ph.D., senior author of the study. "This is quite unusual; potassium channels normally don’t play a direct role in the activation of sensory neurons."
Humans have shrunken, seemingly vestigial VNOs, but still exhibit instinctive, pre-programmed behaviors relating to reproduction and aggression. Scientists hope that an understanding of how the VNO works in mice and other lower mammals will provide clues to how these innate behaviors are triggered in humans.
The VNO works in much the same way as the main olfactory organ that provides the sense of smell. Its neurons and their input stalks, known as dendrites, are studded with specialized receptors that can be activated by contact with specific messenger-chemicals called pheromones, found mostly in body fluids. When activated, VNO receptors cause adjacent ion channels to open or close allowing ions to flood into or out of a neuron. These inflows and outflows of electric charge create voltage surges that can activate a VNO neuron, so that it signals to the brain to turn on a specific behavior.
Filed under science neuroscience brain psychology potassium ion channel vomeronasal organ sex aggression behavior neuron
Science of Eyewitness Memory Enters Courtroom
Science has prevailed over injustice in the state of New Jersey, where all jurors will soon learn about memory’s unreliability and the limits of eyewitness testimony.
According to instructions issued July 19 by New Jersey’s Supreme Court, judges must tell jurors that “human memory is not foolproof,” and enumerate the many ways in which eyewitness recall can be distorted or mistaken.
Filed under brain eyewitness testimony forensics memory neuroscience psychology science justice
Can bacteria fight brain cancer?
The thinking behind an approach that has caused trouble in California.
Last week, the Sacramento Bee reported that two neurosurgeons at the University of California, Davis, had been banned from research on humans after deliberately infecting three terminally ill cancer patients with pathogenic bacteria in an attempt to treat them. All three died, two showing complications from the infection. Nature explores what happened and the science behind it.
Filed under bacteria brain cancer infection medicine neuroscience research science neurosurgery
26 July 2012
Emotional problems in childhood are common. Approximately 8 to 22 percent of children suffer from anxiety, often combined with other conditions such as depression. However, most existing therapies are not designed to treat coexisting psychological problems and are therefore not very successful in helping children with complex emotional issues.
To develop a more effective treatment for co-occurring youth anxiety and depression, University of Miami psychologist Jill Ehrenreich-May and her collaborator Emily L. Bilek analyzed the efficacy and feasibility of a novel intervention created by the researchers, called Emotion Detectives Treatment Protocol (EDTP). Preliminary findings show a significant reduction in the severity of anxiety and depression after treatment, as reported by the children and their parents.
“We are very excited about the potential of EDTP,” says Ehrenreich-May, associate professor of psychology in the College of Arts and Sciences at UM and principal investigator of the study. “Not only could the protocol better address the needs of youth with commonly co-occurring disorders and symptoms, it may also provide additional benefits to mental health professionals,” she says. “EDTP offers a more unified approach to treatment that, we hope, will allow for an efficient and cost-effective treatment option for clinicians and clients alike.”
Emotion Detectives Treatment Program is an adaptation of two treatment protocols developed for adults and adolescents, the Unified Protocols. The program implements age-appropriate techniques that deliver education about emotions and how to manage them, strategies for evaluating situations, problem-solving skills, behavior activation (a technique to reduce depression), and parent training.
In the study, 22 children ages 7 to 12 with a principal diagnosis of an anxiety disorder and secondary issues of depression participated in a 15-session weekly group therapy of EDTP. Among participants who completed the protocol (18 out of 22), 14 no longer met criteria for an anxiety disorder at post-treatment. Additionally, among participants who were assigned a depressive disorder before treatment (5 out of 22), only one participant continued to meet such criteria at post-treatment.
Unlike results from previous studies, the presence of depressive symptoms did not predict poorer treatment response. The results also show a high percentage of attendance. The findings imply that EDTP may offer a better treatment option for children experiencing anxiety and depression.
“Previous research has shown that depressive symptoms tend to weaken treatment response for anxiety disorders. We were hopeful that a broader, more generalized approach would better address this common co-occurrence,” says Bilek, doctoral candidate in clinical psychology at UM and co-author of the study. “We were not surprised to find that the EDTP had equivalent outcomes for individuals with and without elevated depressive symptoms, but we were certainly pleased to find that this protocol may address this important issue.”
The study, titled “An Open Trial Investigation of a Transdiagnostic Group Treatment for Children with Anxiety and Depressive Symptoms,” is published online ahead of print in the journal Behavior Therapy.
The team is currently recruiting participants for a randomized controlled trial comparing the EDTP to another group treatment protocol for anxiety disorders. For more information, please contact the study coordinators at www.miami.edu/childanxiety.
Source: ScienceBlog
Filed under science neuroscience psychology emotions childhood depression anxiety research
The Omega Current
Mutation of voltage-sensor domains (VSDs) can sometimes lead to ions leaking across the membrane through the VSDs themselves. Ion conduction through the mutated VSD of the Shaker Kv channel was coined the “omega current” in 2005 by Tombola, Pathak and Isacoff (Tombola et al., 2005). Many different mutations have been identified that result in current leaking through VSDs in many different channels. This current can be carried by a variety of ions including H+, Li+, K+, Cs+ and guanidinium. It has also been shown that naturally occurring mutations in VSDs that result in omega current leak can lead to channelopathies (diseases caused by malfunctioning ion channels, learn more about them out on wikipedia). In this post I will discuss a mutation of the Shaker Kv channel that results in omega current leak. I will address how this current arises and briefly what it can tell us about the mechanism of voltage-sensing.
Filed under science neuroscience ion channels omega current potassium protein
