The researchers from Lancaster University have found that those with the degenerative brain disease have difficulty with one particular test. They also found that the inability to carry out the tests in those who had already been diagnosed with Alzheimer’s was linked to lower memory function.
Photo: ALAMY
Dr Trevor Crawford said the latest results were potentially exciting. They showed, for the first time, a physical connection with the memory impairment that so often is the first noticeable symptom in Alzheimer’s.
Dr Crawford, of the department of Psychology and the Centre for Ageing Research, Lancaster University, said: “The diagnosis of Alzheimer’s disease is currently heavily dependent on the results of a series of lengthy neuropsychological tests.
"However, patients with a dementia often find that these tests are difficult to complete due to a lack of clear understanding and lapse in their attention or motivation.
"Over the last 10 years, researchers in laboratories around the world have been working on an alternative approach based on the brain’s control of the movements of the eye as a tool for investigating cognitive abilities, such as attention, cognitive inhibition and memory."
During the study, 18 patients with Alzheimer’s disease, 25 patients with Parkinson’s disease, 17 healthy young people and 18 healthy older people were asked to follow the movements of light on a computer monitor. In some instances they were asked to look away from the light. Detailed eye–tracking measurements showed stark contrasts in results.
Patients with Alzheimer’s made errors on the task when they were asked to look away from the light. They were unable correct those errors, despite being able to respond normally when they were asked to look towards the light.
These uncorrected errors were 10 times more frequent in the Alzheimers’ patients than the control groups. Researchers also measured memory function among those Alzheimer’s patients who found the test difficult and were able to show a clear correlation with lower memory function. Dr Crawford added: “The light tracking test could play a vital role in the diagnosis of Alzheimer’s.”
(Source: telegraph.co.uk)
Filed under science neuroscience brain psychology alzheimer's alzheimer disease vision
Women with Alzheimer’s show worse mental deterioration than men with the disease, even when at the same stage of the condition, according to researchers from the University of Hertfordshire.
In the paper published in the Journal of Clinical and Experimental Neuropsychology, the researchers discovered that men with Alzheimer’s consistently and significantly performed better than women with the disease across the five cognitive areas they examined. Most remarkably, the verbal skills of women with Alzheimer’s are worse when compared to men with the disease, which is a striking difference to the profile for the healthy population where females have a distinct advantage.
Filed under alzheimer alzheimer's disease brain cognition neuroscience psychology science performance
The man who holds the record for the world’s lowest voice can hit notes so low that only animals as massive as elephants are able to hear them. U.S. singer Tim Storms can reach notes as low as G-7 (0.189Hz). That’s a remarkable 8 octaves below the lowest G on a piano. So low, in fact, that even Storms himself cannot hear it.
Filed under infrasounds larynx neuroscience science vocalizations vocals voice production
A team of University of Minnesota biomedical engineers and researchers from Mayo Clinic published a groundbreaking study that outlines how a new type of non-invasive brain scan taken immediately after a seizure gives additional insight into possible causes and treatments for epilepsy patients. The new findings could specifically benefit millions of people who are unable to control their epilepsy with medication.
The research was published online in Brain, a leading international journal of neurology.
Professor Bin He discusses his research on a new type of non-invasive brain scan that gives additional insight into possible causes and treatments for epilepsy patients.
Filed under epilepsy brain neuroscience psychology treatment science
August 24, 2012 By Barbara Bronson Gray
(HealthDay)—Whether it’s an email from an unknown gentleman on another continent pleading for money or a financial scammer selling a promising penny stock, the young and old tend to be more easily duped than middle-aged people.
Changes in this region could explain why seniors, children are less doubting.
Now, researchers have pinpointed the area of the brain responsible for this gullibility and have theorized why it makes children, teens and seniors less likely to doubt.
The ventromedial area of the prefrontal cortex of the brain—a softball-sized lobe in the front of your head, just above your eyes—appears to be responsible for allowing you to pause after hearing or reading something and consider whether it’s true, according to a study published recently in the journal Frontiers in Neuroscience.
Read more …
Filed under brain gullibility neuroscience psychology science
Most experimental cancer drugs never make it to market because they don’t help enough people in early clinical trials. But even in “failed” drug trials, researchers may find that a few patients see their tumors shrink dramatically. Since it’s not clear why some respond but most don’t, researchers typically shake their heads and move on. But researchers today report that by sequencing the entire genome of one outlier patient’s tumor, they learned why her cancer disappeared when she took an experimental drug that didn’t help others. That drug now has a new lease on life for this cancer, and such testing may help revive other cancer drugs that showed promise in lab studies but initially failed in clinical testing.
Read more
Filed under science neuroscience cancer genomics genome drug trials
Early fruits of the collaboration between the Genome 10K project and Beijing Genomics Institute (BGI) to sequence 100 vertebrate species have resulted in the sequencing and release of the genome of one of naturalist Charles Darwin’s Galápagos finches, the medium ground finch Geospiza fortis.
This finch genome, the first of the BGI-Genome 10K collaboration to be made available through the UCSC Genome Browser, represents both a scientific and a symbolic advancement, according to Erich Jarvis, Duke University associate professor who studies the neurobiology of vocal learning in songbirds.
Endemic to the subtropical or tropical dry forests and shrublands of the Galápagos Islands this species evolves rapidly in response to environmental changes. ”These finches are of great historical significance, but when Darwin first studied these birds, he was unlikely to have envisioned how this species would become a perfect model to study evolution in action,” said Goujie Zhang, BGI’s associate director of research. “Having the reference genome of this species has opened the door for carrying out studies that can look at real-time evolutionary changes on a genomic level of all of these enigmatic species.”
(Image by: Petr Baum)
Filed under birds evolution finch genomics science biology neuroscience
The co-founder of Alcoholics Anonymous (AA) believed LSD could be used to cure alcoholics and credited the drug with helping his own recovery from often debilitating depression, according to new research.
About 20 years after setting up the Ohio-based sobriety movement in 1935, Bill Wilson came to believe that LSD could help “cynical alcoholics” achieve a “spiritual awakening” and start on the path to recovery.
The discovery that Wilson considered using the drug as an aid to recovery for addicts was made by Don Lattin, author of a book to be published in October by the University of California Press, entitled Distilled Spirits.
Filed under science neuroscience brain psychology LSD alcohol
ScienceDaily (Aug. 23, 2012) — We use language every day to express our emotions, but can this language actually affect what and how we feel? Two new studies from Psychological Science, a journal of the Association for Psychological Science, explore the ways in which the interaction between language and emotion influences our well-being.
Putting Feelings into Words Can Help Us Cope with Scary Situations
Katharina Kircanski and colleagues at the University of California, Los Angeles investigated whether verbalizing a current emotional experience, even when that experience is negative, might be an effective method for treating for people with spider phobias. In an exposure therapy study, participants were split into different experimental groups and they were instructed to approach a spider over several consecutive days.
One group was told to put their feelings into words by describing their negative emotions about approaching the spider. Another group was asked to ‘reappraise’ the situation by describing the spider using emotionally neutral words. A third group was told to talk about an unrelated topic (things in their home) and a fourth group received no intervention. Participants who put their negative feelings into words were most effective at lowering their levels of physiological arousal. They were also slightly more willing to approach the spider. The findings suggest that talking about your feelings — even if they’re negative — may help you to cope with a scary situation.
Unlocking Past Emotion: The Verbs We Use Can Affect Mood and Happiness
Our memory for events is influenced by the language we use. When we talk about a past occurrence, we can describe it as ongoing (I was running) or already completed (I ran). To investigate whether using these different wordings might affect our mood and overall happiness, Will Hart of the University of Alabama conducted four experiments in which participants either recalled or experienced a positive, negative, or neutral event. They found that people who described a positive event with words that suggested it was ongoing felt more positive. And when they described a negative event in the same way, they felt more negative.
The authors conclude that one potential way to improve mood could be to talk about negative past events as something that already happened as opposed to something that was happening.
Source: Science Daily
Filed under science neuroscience psychology brain language emotion
Russian brains behind closest ever AI attempt
Russian scientists are closer than they have ever been to creating artificial intelligence. The program called “Eugene” has almost passed the famous Turing test, which checks a machine’s ability to exhibit intelligent behavior.
The program-emulating a personality of a 13-year old boy was exhibited at an international science contest in the United Kingdom along with four other programs.
Even with the exacting criteria, “Eugene” has left all its competitors far behind.
The test was designed by mathematician and computer scientist, Alan Turing over 60 years ago. During the examination a human judge engages in a text conversation with a machine and an actual human being without seeing them. If the judge fails to tell the machine from the human in at least 30 percent of the answers, the program passes.
So far no program has managed to pass successfully but Russia’s “Eugene” has come strikingly close. It deceived human judges in 29,2 percent of the answers.
A total of 29 judges took part in the test with some 150 dialogues taking place.
Filed under AI Alan Turing Eugene brain neuroscience science technology Turing test
