Neuroscience

Articles and news from the latest research reports.

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FOOTBALL teams of the future — even high school squads on limited budgets — may someday have a new tool to check players for brain injuries. It’s a special form of headgear, packed with sensors that read the brain waves of athletes after they come off the field, thus detecting changes caused by the trauma of hard knocks.
The compact, portable sensors decipher neural activity by measuring changes in the brain’s tiny magnetic field. These small magnetometers — still in the laboratory and in prototype — have yet to be tried on athletes. But their potential is enormous for brain imaging and for inexpensive monitoring of brain diseases, as well as for many other applications like the control of prosthetics, said Dr. José Luis Contreras-Vidal, a professor of electrical and computer engineering at the University of Houston.

FOOTBALL teams of the future — even high school squads on limited budgets — may someday have a new tool to check players for brain injuries. It’s a special form of headgear, packed with sensors that read the brain waves of athletes after they come off the field, thus detecting changes caused by the trauma of hard knocks.

The compact, portable sensors decipher neural activity by measuring changes in the brain’s tiny magnetic field. These small magnetometers — still in the laboratory and in prototype — have yet to be tried on athletes. But their potential is enormous for brain imaging and for inexpensive monitoring of brain diseases, as well as for many other applications like the control of prosthetics, said Dr. José Luis Contreras-Vidal, a professor of electrical and computer engineering at the University of Houston.

Filed under brain brain injury magnetometers neuroscience science technology athletes sports

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Researchers at the Norwegian University of Science and Technology (NTNU) are combining two of the best-known approaches to automatic speech recognition to build a better and language-independent speech-to-text algorithm that can recognize the language being spoken in under a minute, transcribe languages on the brink of extinction, and make the dream of ever present voice-controlled electronics just a little bit closer.
Achieving accurate, real-time speech recognition is no easy feat. Even assuming that the sound acquired by a device can be completely stripped of background noise (which isn’t always the case), there is hardly a one-to-one correspondence between the waveform detected by a microphone and the phoneme being spoken. Different people speak the same language with different nuances – accents, lisps and other articulation defects. Other factors such as age, gender, health and education also play a big role in altering the sound that reaches the microphone.
The NTNU researchers are now pioneering an approach that, if it can be fully exploited, may lead to a big leap in the performance of speech-to-text applications. They demonstrated that the mechanics of human speech are fundamentally the same across all people and across all languages, and they are now training a computer to analyze the pressure of sound waves captured by the microphone to determine which parts of the speech organs were used to produce a phoneme.

Researchers at the Norwegian University of Science and Technology (NTNU) are combining two of the best-known approaches to automatic speech recognition to build a better and language-independent speech-to-text algorithm that can recognize the language being spoken in under a minute, transcribe languages on the brink of extinction, and make the dream of ever present voice-controlled electronics just a little bit closer.

Achieving accurate, real-time speech recognition is no easy feat. Even assuming that the sound acquired by a device can be completely stripped of background noise (which isn’t always the case), there is hardly a one-to-one correspondence between the waveform detected by a microphone and the phoneme being spoken. Different people speak the same language with different nuances – accents, lisps and other articulation defects. Other factors such as age, gender, health and education also play a big role in altering the sound that reaches the microphone.

The NTNU researchers are now pioneering an approach that, if it can be fully exploited, may lead to a big leap in the performance of speech-to-text applications. They demonstrated that the mechanics of human speech are fundamentally the same across all people and across all languages, and they are now training a computer to analyze the pressure of sound waves captured by the microphone to determine which parts of the speech organs were used to produce a phoneme.

Filed under speech recognition technology science neuroscience speech

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A typical five-month-old infant has hardly figured out how to sit up yet — even crawling may be months away — but there are a few babies who already know how to drive. They’re steering their very own mobile robots. 
The robots are designed to allow babies with disabilities to move around independently, at the same age their peers might learn to crawl.  Whether they use robots or their own limbs, starting to move may be an important part of baby brain development, some childhood specialists think. Researchers don’t want kids with cerebral palsy or other movement disorders to miss out. 
"We think that babies with disabilities are missing an opportunity for learning that typically developing babies have," said Carole Dennis, a professor occupational therapy at Ithaca College in New York.

A typical five-month-old infant has hardly figured out how to sit up yet — even crawling may be months away — but there are a few babies who already know how to drive. They’re steering their very own mobile robots. 

The robots are designed to allow babies with disabilities to move around independently, at the same age their peers might learn to crawl.  Whether they use robots or their own limbs, starting to move may be an important part of baby brain development, some childhood specialists think. Researchers don’t want kids with cerebral palsy or other movement disorders to miss out. 

"We think that babies with disabilities are missing an opportunity for learning that typically developing babies have," said Carole Dennis, a professor occupational therapy at Ithaca College in New York.

Filed under baby-drivable robots brain development disability neuroscience robotics robots science technology WeeBot

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Baby songbirds learn to sing by imitation, just as human babies do. So researchers at Harvard and Utrecht University, in the Netherlands, have been studying the brains of zebra finches—red-beaked, white-breasted songbirds—for clues to how young birds and human infants learn vocalization on a neuronal level.
While a baby bird mimicking the chirps of his “tutor” may seem far removed from human learning, the researchers at the two universities found that the songs of the birds and human language are both processed in similar areas on the left sides of the two very different brains. The discovery was published last month in the Proceedings of the National Academy of Sciences.

Baby songbirds learn to sing by imitation, just as human babies do. So researchers at Harvard and Utrecht University, in the Netherlands, have been studying the brains of zebra finches—red-beaked, white-breasted songbirds—for clues to how young birds and human infants learn vocalization on a neuronal level.

While a baby bird mimicking the chirps of his “tutor” may seem far removed from human learning, the researchers at the two universities found that the songs of the birds and human language are both processed in similar areas on the left sides of the two very different brains. The discovery was published last month in the Proceedings of the National Academy of Sciences.

Filed under birds evolution neuroscience science lateralization vocalization language brain birdsong

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DNA could have existed long before life itself

24 August 2012 by Michael Marshall

THE latest twist in the origin-of-life tale is double helical. Chemists are close to demonstrating that the building blocks of DNA can form spontaneously from chemicals thought to be present on the primordial Earth. If they succeed, their work would suggest that DNA could have predated the birth of life.

Lurking at the dawn of time (Image: Snorri Gunnarsson/Flickr/Getty)

DNA is essential to almost all life on Earth, yet most biologists think that life began with RNA. Just like DNA, it stores genetic information. What’s more, RNA can fold into complex shapes that can clamp onto other molecules and speed up chemical reactions, just like a protein, and it is structurally simpler than DNA, so might be easier to make.

After decades of trying, in 2009 researchers finally managed to generate RNA using chemicals that probably existed on the early Earth. Matthew Powner, now at University College London, and his colleagues synthesised two of the four nucleotides that make up RNA. Their achievement suggested that RNA may have formed spontaneously - powerful support for the idea that life began in an “RNA world”.

Read more …

Filed under science biology DNA life RNA neuroscience DNA nucleotides biochemistry

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Slinging political dirt may be something both sides engage in during election season, but for some voters that metaphor may reveal something more fundamental about their view of the world.
According to a study in the September 2012 issue of Social Psychology & Personality Science claims to have found “a positive relationship between disgust sensitivity and political conservatism” — that is, if you’re conservative, you’re more likely to be disgusted by things you experience. It’s a correlation that holds in the samples they tested in the United States and from the rest of the world.

Slinging political dirt may be something both sides engage in during election season, but for some voters that metaphor may reveal something more fundamental about their view of the world.

According to a study in the September 2012 issue of Social Psychology & Personality Science claims to have found “a positive relationship between disgust sensitivity and political conservatism” — that is, if you’re conservative, you’re more likely to be disgusted by things you experience. It’s a correlation that holds in the samples they tested in the United States and from the rest of the world.

Filed under brain conservatives neuroscience politics psychology science voters

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Most Neanderthals were right handed, just like modern humans, and this tendency suggests that they may have had the capacity for speech, new research claims.
A new investigation by Professor Frayer and an international team led by Virginie Volpato of the Senckenberg Institute in Frankfurt, Germany, has confirmed Regourdou’s right-handedness by looking more closely at the robustness of the arms and shoulders, and comparing it with scratches on his teeth.

'We’ve been studying scratch marks on Neanderthal teeth, but in all cases they were isolated teeth, or teeth in mandibles not directly associated with skeletal material,' said Professor Frayer.'This is the first time we can check the pattern that’s seen in the teeth with the pattern that’s seen in the arms. We did more sophisticated analysis of the arms — the collarbone, the humerus, the radius and the ulna — because we have them on both sides. And we looked at cortical thickness and other biomechanical measurements. All of them confirmed that everything was more robust on the right side then the left.'

Most Neanderthals were right handed, just like modern humans, and this tendency suggests that they may have had the capacity for speech, new research claims.

A new investigation by Professor Frayer and an international team led by Virginie Volpato of the Senckenberg Institute in Frankfurt, Germany, has confirmed Regourdou’s right-handedness by looking more closely at the robustness of the arms and shoulders, and comparing it with scratches on his teeth.

'We’ve been studying scratch marks on Neanderthal teeth, but in all cases they were isolated teeth, or teeth in mandibles not directly associated with skeletal material,' said Professor Frayer.

'This is the first time we can check the pattern that’s seen in the teeth with the pattern that’s seen in the arms. We did more sophisticated analysis of the arms — the collarbone, the humerus, the radius and the ulna — because we have them on both sides. And we looked at cortical thickness and other biomechanical measurements. All of them confirmed that everything was more robust on the right side then the left.'

Filed under Regourdou handedness language laterality neanderthals neuroscience science speech brain lateralisation

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Astrocytes Control the Generation of New Neurons from Neural Stem Cells

August 24th, 2012

Researchers from the Laboratory of astrocyte biology and CNS regeneration headed by Prof. Milos Pekny just published a research article in a prestigious journal Stem Cells on the molecular mechanism that controls generation of new neurons in the brain.

Astrocytes are cells that have many functions in the central nervous system, such as the control of neuronal synapses, blood flow, or the brain’s response to neurotrauma or stroke.

Reduces brain tissue damage

Prof. Pekny’s laboratory together with collaborators have earlier demonstrated that astrocytes reduce the brain tissue damage after stroke and that the integration of transplanted neural stem cells can be largely improved by modulating the activity of astrocytes.

Generation of new neurons

In their current study, the Sahlgrenska Academy researchers show how astrocytes control the generation of new neurons in the brain. An important contribution to this project came from Åbo Academy, one of Sahlgrenska’s traditional collaborative partners.

“In the brain, astrocytes control how many new neurons are formed from neural stem cells and survive to integrate into the existing neuronal networks. Astrocytes do this by secreting specific molecules but also by much less understood direct cell-cell interactions with stem cells”, says Prof. Milos Pekny.

Image shows GFAP stained cortex from a TgAPP mouse showing activated astrocytes from a different study.

Important regulator

“Astrocytes are in physical contact with neural stem cells and we have shown that they signal through the Notch pathway to stem cells to keep the birth rate of new neurons low. We have also shown that the intermediate filament system of astrocytes is an important regulator of this process. It seems that astrocyte intermediate filaments can be used as a target to increase the birthrate of new neurons.”

Target for future therapies

“We are starting to understand some of the cellular and molecular mechanisms behind the control of neurogenesis. Neurogenesis is one of the components of brain plasticity, which plays a role in the learning process as well as in the recovery after brain injury or stroke. This work helps us to understand how plasticity and regenerative response can be therapeutically promoted in the future”, says Prof. Milos Pekny.

Source: Neuroscience News

Filed under astrocytes neuron stem cells brain neuroscience science psychology CNS

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